NBP254379G
Von Willebrand Factor Antibody (F8/86), DyLight 488, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP254379G-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP254379G - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Von Willebrand Factor
Classification
Monoclonal
Conjugate
DyLight 488
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
VWF
Immunogen
Von Willebrand Factor isolated from human plasma (Uniprot: P04275)
Quantity
0.1 mL
Gene ID (Entrez)
7450.0
Target Species
Human
Isotype
IgG1 κ
Applications
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
F8/86
Dilution
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias
coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
Host Species
Mouse
Purification Method
Protein A or G purified
Primary or Secondary
Primary
Test Specificity
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Content And Storage
Store at 4°C in the dark.
Description
- Von Willebrand Factor Monoclonal specifically detects Von Willebrand Factor in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: Von Willebrand Factor
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: VWF
Immunogen: Von Willebrand Factor isolated from human plasma (Uniprot: P04275)
Quantity: 0.1 mL
Gene ID (Entrez): 7450.0
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: F8/86
Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
Host Species: Mouse
Purification Method: Protein A or G purified
Primary or Secondary: Primary
Test Specificity: von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Content And Storage: Store at 4°C in the dark.
Antigen:
Von Willebrand Factor
Classification:
Monoclonal
Conjugate:
DyLight 488
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
VWF
Immunogen:
Von Willebrand Factor isolated from human plasma (Uniprot: P04275)
Quantity:
0.1 mL
Gene ID (Entrez):
7450.0
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
F8/86
Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF
Host Species:
Mouse
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Content And Storage:
Store at 4°C in the dark.
Antigen: PSGL-1/CD162
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: SELPLG
Immunogen: Recombinant human PSGL-1/CD162 protein (Uniprot: Q14242)
Quantity: 0.1 mL
Gene ID (Entrez): 6404
Target Species: Human
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: PSGL1/1601
Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: CD162, CD162 antigen, P-selectin glycoprotein ligand 1, PSGL1, PSGL-1cutaneous lymphocyte-associated associated antigen, selectin P ligandCLA
Host Species: Mouse
Purification Method: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Store at 4°C in the dark.
Antigen:
PSGL-1/CD162
Classification:
Monoclonal
Conjugate:
DyLight 488
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
SELPLG
Immunogen:
Recombinant human PSGL-1/CD162 protein (Uniprot: Q14242)
Quantity:
0.1 mL
Gene ID (Entrez):
6404
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
PSGL1/1601
Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
CD162, CD162 antigen, P-selectin glycoprotein ligand 1, PSGL1, PSGL-1cutaneous lymphocyte-associated associated antigen, selectin P ligandCLA
Host Species:
Mouse
Purification Method:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4°C in the dark.
Antigen: CD31/PECAM-1
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: PECAM1
Immunogen: Recombinant full-length human CD31/PECAM-1 protein (Uniprot: P16284)
Quantity: 0.1 mL
Gene ID (Entrez): 5175
Target Species: Human
Isotype: IgG
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: C31/1395R
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA′, PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule-1, platelet/endothelial cell adhesion molecule
Host Species: Rabbit
Purification Method: __
Primary or Secondary: Primary
Test Specificity: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 monoclonal antibody reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Content And Storage: Store at 4°C in the dark.
Antigen:
CD31/PECAM-1
Classification:
Monoclonal
Conjugate:
DyLight 488
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
PECAM1
Immunogen:
Recombinant full-length human CD31/PECAM-1 protein (Uniprot: P16284)
Quantity:
0.1 mL
Gene ID (Entrez):
5175
Target Species:
Human
Isotype:
IgG
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
C31/1395R
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA′, PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule-1, platelet/endothelial cell adhesion molecule
Host Species:
Rabbit
Purification Method:
__
Primary or Secondary:
Primary
Test Specificity:
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 monoclonal antibody reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Content And Storage:
Store at 4°C in the dark.
Antigen: CD11c
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: ITGAX
Immunogen: Recombinant human CD11c protein fragment (aa 637-827) (exact sequence is proprietary) (Uniprot: P20702)
Quantity: 0.1 mL
Gene ID (Entrez): 3687
Target Species: Human
Isotype: IgG2b κ
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: ITGAX/1284
Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: 95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6
Host Species: Mouse
Purification Method: __
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
Content And Storage: Store at 4°C in the dark.
Antigen:
CD11c
Classification:
Monoclonal
Conjugate:
DyLight 488
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
ITGAX
Immunogen:
Recombinant human CD11c protein fragment (aa 637-827) (exact sequence is proprietary) (Uniprot: P20702)
Quantity:
0.1 mL
Gene ID (Entrez):
3687
Target Species:
Human
Isotype:
IgG2b κ
Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
ITGAX/1284
Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6
Host Species:
Mouse
Purification Method:
__
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
Content And Storage:
Store at 4°C in the dark.