NBP254429G

CEACAM5/CD66e Antibody (C66/1291), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP254429G-Each-of-1 In Stock ₹ 53,688.90

NBP254429G - Each of 1

₹ 53,688.90

In Stock

Quantity

1

Base Price: ₹ 53,688.90

GST (18%): ₹ 9,664.002

Total Price: ₹ 63,352.902

Antigen

CEACAM5/CD66e

Classification

Monoclonal

Conjugate

DyLight 488

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

CEACAM5

Immunogen

Recombinant full-length human CEACAM5/CD66e protein (Uniprot: P06731)

Primary or Secondary

Primary

Test Specificity

This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This monoclonal antibody does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbladder, urachus, salivary gland, ovary, and endocervix.

Content And Storage

Store at 4°C in the dark.

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

C66/1291

Dilution

Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100

Host Species

Mouse

Quantity

0.1 mL

Gene ID (Entrez)

1048

Target Species

Human

Isotype

IgG1

Description

  • CEACAM5/CD66e Monoclonal specifically detects CEACAM5/CD66e in Human samples
  • It is validated for ELISA, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP254429G

--


Antigen:
CEACAM5/CD66e

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CEACAM5

Immunogen:
Recombinant full-length human CEACAM5/CD66e protein (Uniprot: P06731)

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This monoclonal antibody does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbladder, urachus, salivary gland, ovary, and endocervix.

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
C66/1291

Dilution:
Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
1048

Target Species:
Human

Isotype:
IgG1

Img

Novus Biologicals

NBP254430G

--


Antigen:
Von Willebrand Factor

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
VWF

Immunogen:
Recombinant fragment of human Von Willebrand Factor protein (aa1815-1939) (exact sequence is proprietary) (Uniprot: P04275)

Primary or Secondary:
Primary

Test Specificity:
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
VWF/1465

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
7450.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP254436G

--


Antigen:
Clathrin light chain

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CLTA

Immunogen:
Purified recombinant N-terminal fragment of human Clathrin Light Chain

Primary or Secondary:
Primary

Test Specificity:
Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
CLC/1421

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
clathrin light chain A, clathrin, light chain A, LCA, light polypeptide (Lca)

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
1211

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NBP254438G

--


Antigen:
Serpin A3/alpha 1-Antichymotrypsin

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
SERPINA3

Immunogen:
Recombinant human Serpin A3/alpha 1-Antichymotrypsin protein fragment (around aa 49-187) (exact sequence is proprietary) (Uniprot: P01011)

Primary or Secondary:
Primary

Test Specificity:
It recognizes a protein of 65-76kDa, which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
AACT/1452

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
AACTMGC88254, ACTGIG25, alpha-1-antichymotrypsin, antitrypsin), member 3, Cell growth-inhibiting gene 24/25 protein, growth-inhibiting protein 24, growth-inhibiting protein 25, member 3, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, serine (or cysteine) proteinase inhibitor, clade A, member 3, Serpin A3, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
12

Target Species:
Human

Isotype:
IgG1 κ