NBP254497G

Von Willebrand Factor Antibody (VWF/1767), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP254497G-Each-of-1 In Stock ₹ 55,271.76

NBP254497G - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Von Willebrand Factor

Classification

Monoclonal

Conjugate

DyLight 488

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

VWF

Immunogen

Recombinant fragment (around aa1815-1939) of human Von Willebrand Factor protein (exact sequence is proprietary) (Uniprot: P04275)

Primary or Secondary

Primary

Test Specificity

von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

VWF/1767

Dilution

Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF

Host Species

Mouse

Quantity

0.1 mL

Gene ID (Entrez)

7450

Target Species

Human

Isotype

IgG2b κ

Description

  • Von Willebrand Factor Monoclonal specifically detects Von Willebrand Factor in Human samples
  • It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NBP254497G

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Antigen:
Von Willebrand Factor

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
VWF

Immunogen:
Recombinant fragment (around aa1815-1939) of human Von Willebrand Factor protein (exact sequence is proprietary) (Uniprot: P04275)

Primary or Secondary:
Primary

Test Specificity:
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
VWF/1767

Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
coagulation factor VIII VWF, F8, F8VWF, von Willebrand factor, VWD, vWF

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
7450

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NBP254500G

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Antigen:
Chorionic Gonadotropin alpha Chain (hCG alpha)

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CGA

Immunogen:
Recombinant full-length Chorionic Gonadotropin alpha Chain (hCG alpha) protein (Uniprot: P01215)

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a protein of ∼13kDa, identified as alpha sub-unit of Luteinizing Hormone (LH). Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
LHa/756

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
CGA glycoprotein hormones, alpha polypeptide, CG-ALPHA, FSHA, GPHa, GPHA1, HCG, LHA, TSHA

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
1081

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP254502G

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Antigen:
CD40/TNFRSF5

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CD40

Immunogen:
Recombinant full-length human CD40/TNFRSF5 protein (Uniprot: P25942)

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
C40/1605

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
B cell surface antigen CD40, B-cell surface antigen CD40, Bp50B cell-associated molecule, CD40 antigen, CD40 molecule, TNF receptor superfamily member 5, CD40 type II isoform, CD40L receptor, CDw40, MGC9013, nerve growth factor receptor-related B-lymphocyte activation molecule, p50, TNFRSF5CD40 antigen (TNF receptor superfamily member 5), tumor necrosis factor receptor superfamily member 5, tumor necrosis factor receptor superfamily, member 5

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
958

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP254503G

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Antigen:
Desmin

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
DES

Immunogen:
Recombinant human desmin protein (Uniprot: P17661)

Primary or Secondary:
Primary

Test Specificity:
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
DES/1711

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
CMD1IFLJ41013, CSM1, CSM2, desmin, FLJ12025, FLJ39719, FLJ41793, intermediate filament protein

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
1674

Target Species:
Human, Mouse, Rat, Chicken, Hamster

Isotype:
IgG1 κ