PAX8 Antibody (PAX8/1492), DyLight 488, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP254539G-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP254539G - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
PAX8
Classification
Monoclonal
Conjugate
DyLight 488
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
PAX8
Immunogen
Recombinant fragment (around aa 60-261) of human PAX8 protein (exact sequence is proprietary) (Uniprot: Q06710)
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 62kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
Content And Storage
Store at 4°C in the dark.
Applications
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
PAX8/1492
Dilution
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias
paired box 8, paired box gene 8, paired box protein Pax-8, paired domain gene 8
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Cancer
Gene ID (Entrez)
7849.0
Target Species
Human
Isotype
IgG2b κ
Related Products
Description
- Description PAX8 Monoclonal specifically detects PAX8 in Human samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: PAX8
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: PAX8
Immunogen: Recombinant fragment (around aa 60-261) of human PAX8 protein (exact sequence is proprietary) (Uniprot: Q06710)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 62kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: PAX8/1492
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: paired box 8, paired box gene 8, paired box protein Pax-8, paired domain gene 8
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer
Gene ID (Entrez): 7849.0
Target Species: Human
Isotype: IgG2b κ
Antigen: beta-Catenin
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: CTNNB1
Immunogen: Recombinant chicken beta-Catenin (Uniprot: P35222)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody recognizes a protein of 92kDa, which is identified as beta-catenin. It shows no cross-reaction with gamma-catenin (also known as plakoglobin). The catenins, alpha, beta and gamma bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin was initially described as an E-cadherin-associated protein, and has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin has also been found in complexes with the tumor suppressor protein APC.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: 6F9
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: beta 1 (88kD), beta-catenin, catenin (cadherin-associated protein), beta 1, 88kDa, catenin beta-1, CTNNB, DKFZp686D02253, FLJ25606, FLJ37923
Host Species: Mouse
Purification Method: __
Research Discipline: __
Gene ID (Entrez): 1499
Target Species: Human, Bovine, Canine, Chicken
Isotype: IgG1 κ
Antigen: beta-Catenin
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: CTNNB1
Immunogen: Recombinant chicken beta-Catenin (Uniprot: P35222)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: 15B8
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: beta 1 (88kD), beta-catenin, catenin (cadherin-associated protein), beta 1, 88kDa, catenin beta-1, CTNNB, DKFZp686D02253, FLJ25606, FLJ37923
Host Species: Mouse
Purification Method: __
Research Discipline: __
Gene ID (Entrez): 1499
Target Species: Human, Mouse, Rat, Bovine, Canine, Chicken
Isotype: IgG1 κ