NBP275774
Filaggrin Antibody (FLG/1563) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP275774-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP275774 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Filaggrin
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.
P20930
Gene Symbols
FLG
Immunogen
Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary) (Uniprot: P20930)
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage
Store at 4°C.
Isotype
IgG2b κ
Applications
Immunohistochemistry (Paraffin)
Clone
FLG/1563
Conjugate
Unconjugated
Formulation
10 mM PBS with No Preservative
Gene Alias
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Cytoskeleton Markers
Gene ID (Entrez)
2312.0
Target Species
Human
Form
Purified
Related Products
Description
- Filaggrin Monoclonal specifically detects Filaggrin in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
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Antigen: Filaggrin
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.: P20930
Gene Symbols: FLG
Immunogen: Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary) (Uniprot: P20930)
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Applications: Immunohistochemistry (Paraffin)
Clone: FLG/1563
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 2312.0
Target Species: Human
Form: Purified
Antigen:
Filaggrin
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.:
P20930
Gene Symbols:
FLG
Immunogen:
Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary) (Uniprot: P20930)
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
FLG/1563
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
2312.0
Target Species:
Human
Form:
Purified
Antigen: UCH-L1/PGP9.5
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P09936
Gene Symbols: UCHL1
Immunogen: Recombinant full-length human UCH-L1/PGP9.5 protein (Uniprot: P09936)
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCH-L1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: rUCHL1/775
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: __
Gene ID (Entrez): 7345.0
Target Species: Human, Rat
Form: Purified
Antigen:
UCH-L1/PGP9.5
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P09936
Gene Symbols:
UCHL1
Immunogen:
Recombinant full-length human UCH-L1/PGP9.5 protein (Uniprot: P09936)
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCH-L1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
rUCHL1/775
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
__
Gene ID (Entrez):
7345.0
Target Species:
Human, Rat
Form:
Purified
Antigen: Prostatic Acid Phosphatase/ACPP
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 0.5-1.0 ug/ml
Gene Accession No.: P15309
Gene Symbols: ACP3
Immunogen: Recombinant full-length human Prostatic Acid Phosphatase/ACPP protein (Uniprot: P15309)
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 52kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: rACPP/1338
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: acid phosphatase, prostate, ACP3, ACP-3, EC 3.1.3.2, PAP, prostatic acid phosphatase, prostatic acid phosphotase
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cell Cycle and Replication
Gene ID (Entrez): 55.0
Target Species: Human
Form: Purified
Antigen:
Prostatic Acid Phosphatase/ACPP
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 0.5-1.0 ug/ml
Gene Accession No.:
P15309
Gene Symbols:
ACP3
Immunogen:
Recombinant full-length human Prostatic Acid Phosphatase/ACPP protein (Uniprot: P15309)
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 52kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
rACPP/1338
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
acid phosphatase, prostate, ACP3, ACP-3, EC 3.1.3.2, PAP, prostatic acid phosphatase, prostatic acid phosphotase
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cell Cycle and Replication
Gene ID (Entrez):
55.0
Target Species:
Human
Form:
Purified
Antigen: GP2
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P55259
Gene Symbols: GP2
Immunogen: Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary) (Uniprot: P55259)
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Content And Storage: Store at 4°C.
Isotype: IgG2a κ
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: GP2/1803
Conjugate: Unconjugated
Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Alias: DKFZp779K0533, glycoprotein 2 (zymogen granule membrane), pancreatic secretory granule membrane major glycoprotein GP2, pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: __
Gene ID (Entrez): 2813.0
Target Species: Human
Form: Purified
Antigen:
GP2
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P55259
Gene Symbols:
GP2
Immunogen:
Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary) (Uniprot: P55259)
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Content And Storage:
Store at 4°C.
Isotype:
IgG2a κ
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
GP2/1803
Conjugate:
Unconjugated
Formulation:
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
DKFZp779K0533, glycoprotein 2 (zymogen granule membrane), pancreatic secretory granule membrane major glycoprotein GP2, pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
__
Gene ID (Entrez):
2813.0
Target Species:
Human
Form:
Purified