NBP47857B
Androgen R/NR3C4 Antibody (AR441 + DHTR/882), Biotin, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP47857B-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP47857B - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Androgen R/NR3C4
Classification
Monoclonal
Conjugate
Biotin
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
AR
Immunogen
A synthetic peptide, aa 302-318 of human Androgen R/NR3C4 (Androgen R/NR3C4441); Recombinant human DHTR protein (DHTR/882) (Uniprot: P10275)
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This monoclonal antibody is superb for staining of formalin/paraffin tissues.
Content And Storage
Store at 4C in the dark.
Isotype
IgG1 κ
Applications
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone
AR441 + DHTR/882
Dilution
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Breast Cancer, Cancer, Cellular Markers, Phospho Specific
Gene ID (Entrez)
367
Target Species
Human, Mouse (Negative)
Form
Purified
Related Products
Description
- Androgen R/NR3C4 Monoclonal specifically detects Androgen R/NR3C4 in Human, Mouse (Negative) samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: Androgen R/NR3C4
Classification: Monoclonal
Conjugate: Biotin
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: AR
Immunogen: A synthetic peptide, aa 302-318 of human Androgen R/NR3C4 (Androgen R/NR3C4441); Recombinant human DHTR protein (DHTR/882) (Uniprot: P10275)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This monoclonal antibody is superb for staining of formalin/paraffin tissues.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: AR441 + DHTR/882
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Breast Cancer, Cancer, Cellular Markers, Phospho Specific
Gene ID (Entrez): 367
Target Species: Human, Mouse (Negative)
Form: Purified
Antigen:
Androgen R/NR3C4
Classification:
Monoclonal
Conjugate:
Biotin
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
AR
Immunogen:
A synthetic peptide, aa 302-318 of human Androgen R/NR3C4 (Androgen R/NR3C4441); Recombinant human DHTR protein (DHTR/882) (Uniprot: P10275)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This monoclonal antibody is superb for staining of formalin/paraffin tissues.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
AR441 + DHTR/882
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Breast Cancer, Cancer, Cellular Markers, Phospho Specific
Gene ID (Entrez):
367
Target Species:
Human, Mouse (Negative)
Form:
Purified
Antigen: WT1
Classification: Monoclonal
Conjugate: Biotin
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: WT1
Immunogen: Recombinant full length human WT1 protein (WT1/857); Recombinant fragment aa1-181 of human WT1 (6F-H2) (Uniprot: P19544)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: WT1/857 + 6F-H2
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: AWT1, NPHS4GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT-2, WT33
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Angiogenesis, Cancer, Cell Cycle and Replication, Cellular Markers, Chromatin Research, Tumor Suppressors
Gene ID (Entrez): 7490
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
WT1
Classification:
Monoclonal
Conjugate:
Biotin
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
WT1
Immunogen:
Recombinant full length human WT1 protein (WT1/857); Recombinant fragment aa1-181 of human WT1 (6F-H2) (Uniprot: P19544)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
WT1/857 + 6F-H2
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
AWT1, NPHS4GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT-2, WT33
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Angiogenesis, Cancer, Cell Cycle and Replication, Cellular Markers, Chromatin Research, Tumor Suppressors
Gene ID (Entrez):
7490
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: Nucleolin
Classification: Monoclonal
Conjugate: Biotin
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: NCL
Immunogen: Lysate of SU-DHL-1 Nuclei (364-5); Recombinant human NCL protein (NCL/902) (Uniprot: P19338 )
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of ∼76kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. This monoclonal antibody can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: 364-5 + NCL/902
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: C23, FLJ45706, FLJ59041, nucleolin, Protein C23
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cell Cycle and Replication, Chromatin Research, Core ESC Like Genes, DNA Repair, DNA replication Transcription Translation and Splicing, Phospho Specific, Stem Cell Markers
Gene ID (Entrez): 4691
Target Species: Human, Bovine (Negative), Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
Nucleolin
Classification:
Monoclonal
Conjugate:
Biotin
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
NCL
Immunogen:
Lysate of SU-DHL-1 Nuclei (364-5); Recombinant human NCL protein (NCL/902) (Uniprot: P19338 )
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of ∼76kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. This monoclonal antibody can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
364-5 + NCL/902
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
C23, FLJ45706, FLJ59041, nucleolin, Protein C23
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cell Cycle and Replication, Chromatin Research, Core ESC Like Genes, DNA Repair, DNA replication Transcription Translation and Splicing, Phospho Specific, Stem Cell Markers
Gene ID (Entrez):
4691
Target Species:
Human, Bovine (Negative), Mouse (Negative), Rat (Negative)
Form:
Purified
Antigen: p21/CIP1/CDKN1A
Classification: Monoclonal
Conjugate: Biotin
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CDKN1A
Immunogen: Recombinant full-length human p21/CIP1/CDKN1A protein (CIP1/823); Human recombinant p21 protein (DCS-60.2) (Uniprot: P38936)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This monoclonal antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Content And Storage: Store at 4C in the dark.
Isotype: IgG2a κ
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: CIP1/823 + DCS-60.2
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, DNA Repair, Phospho Specific
Gene ID (Entrez): 1026
Target Species: Human, Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
p21/CIP1/CDKN1A
Classification:
Monoclonal
Conjugate:
Biotin
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CDKN1A
Immunogen:
Recombinant full-length human p21/CIP1/CDKN1A protein (CIP1/823); Human recombinant p21 protein (DCS-60.2) (Uniprot: P38936)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This monoclonal antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2a κ
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
CIP1/823 + DCS-60.2
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, DNA Repair, Phospho Specific
Gene ID (Entrez):
1026
Target Species:
Human, Mouse (Negative), Rat (Negative)
Form:
Purified