NBP47983B

Cytokeratin 8/18 Antibody (KRT8/803 + KRT18/835), Biotin, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP47983B-Each-of-1 In Stock ₹ 55,271.76

NBP47983B - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Cytokeratin 8/18

Classification

Monoclonal

Conjugate

Biotin

Formulation

PBS with 0.05% Sodium Azide

Gene Alias

CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Cancer, Cytoskeleton Markers, Phospho Specific

Gene ID (Entrez)

3856

Target Species

Human

Form

Purified

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone

KRT8/803 + KRT18/835

Dilution

Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Accession No.

P05787, P05783

Gene Symbols

KRT8

Immunogen

Recombinant full-length human KRT8 protein (KRT8/803); Recombinant full-length human KRT18 protein (KRT18/835)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immuno-histochemical staining with this monoclonal antibody is indistinguishable from that obtained with monoclonal antibody 5D3.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Description

  • Cytokeratin 8/18 Monoclonal specifically detects Cytokeratin 8/18 in Human samples
  • It is validated for Simple Western, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NBP47983B

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Antigen:
Cytokeratin 8/18

Classification:
Monoclonal

Conjugate:
Biotin

Formulation:
PBS with 0.05% Sodium Azide

Gene Alias:
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Cytoskeleton Markers, Phospho Specific

Gene ID (Entrez):
3856

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
KRT8/803 + KRT18/835

Dilution:
Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Accession No.:
P05787, P05783

Gene Symbols:
KRT8

Immunogen:
Recombinant full-length human KRT8 protein (KRT8/803); Recombinant full-length human KRT18 protein (KRT18/835)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immuno-histochemical staining with this monoclonal antibody is indistinguishable from that obtained with monoclonal antibody 5D3.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

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Novus Biologicals

NBP48000B

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Antigen:
Arginase 1/ARG1/liver Arginase

Classification:
Monoclonal

Conjugate:
Biotin

Formulation:
PBS with 0.05% Sodium Azide

Gene Alias:
arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Cellular Markers, Chromatin Research, Lipid and Metabolism, Myeloid derived Suppressor Cell

Gene ID (Entrez):
383

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
ARG1/1125 + ARG1/1126

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Accession No.:
__

Gene Symbols:
ARG1

Immunogen:
Recombinant human Arginase 1/ARG1/liver Arginase protein fragment (around aa11-97) (exact sequence is proprietary) (Uniprot: P05089 )

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG3 κ

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Novus Biologicals

NBP48013B

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Antigen:
alpha-Fetoprotein/AFP

Classification:
Monoclonal

Conjugate:
Biotin

Formulation:
PBS with 0.05% Sodium Azide

Gene Alias:
Alpha-1-fetoprotein, Alpha-fetoglobulin, alpha-fetoprotein, FETA, HP, HPAFP

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Cancer Stem Cells, GPCR, Stem Cell Markers, Tumor Biomarkers

Gene ID (Entrez):
174

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
C2 + C3 + MBS-12

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Accession No.:
__

Gene Symbols:
AFP

Immunogen:
Recombinant full-length human alpha-Fetoprotein/AFP protein (Uniprot: P02771)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP). This monoclonal antibody is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP48348549

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Antigen:
panCytokeratin

Classification:
Monoclonal

Conjugate:
Janelia Fluor 549

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Alias:
CK1, EHK, EHK1, EPPK, K1, Keratin 1, KRT1, KRT1A, NEPPK

Host Species:
Mouse

Purification Method:
Protein A purified

Research Discipline:
Apoptosis, Cancer, Cell Biology, Cellular Markers, Signal Transduction

Gene ID (Entrez):
3848

Target Species:
Human, Mammalia, Mouse, Rat

Form:
Purified

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
C-11

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Accession No.:
__

Gene Symbols:
KRT1

Immunogen:
This Cytokeratin, pan Antibody (C-11) was developed against a keratin-enriched preparation from human epidermoid carcinoma cell line A431.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This Mouse monoclonal Cytokeratin (Pan-reactive) antibody reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG1