NP140894A32
P2X7/P2RX7 Antibody (Hano43), Alexa Fluor™ 532, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NP140894A32-Each-of-1 | In Stock | ₹ 53,218.32 |
NP140894A32 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,218.32
GST (18%): ₹ 9,579.298
Total Price: ₹ 62,797.618
Antigen
P2X7/P2RX7
Classification
Monoclonal
Conjugate
Alexa Fluor 532
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
P2RX7
Immunogen
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity
0.1 mL
Gene ID (Entrez)
5027.0
Target Species
Mouse
Isotype
IgG2b
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone
Hano43
Dilution
Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species
Rat
Purification Method
Protein G purified
Primary or Secondary
Primary
Test Specificity
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage
Store at 4°C in the dark.
Description
- Description P2X7/P2RX7 Monoclonal specifically detects P2X7/P2RX7 in Mouse samples
- It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.
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Antigen: P2X7/P2RX7
Classification: Monoclonal
Conjugate: Alexa Fluor 532
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mL
Gene ID (Entrez): 5027.0
Target Species: Mouse
Isotype: IgG2b
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: Hano43
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: Protein G purified
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4°C in the dark.
Antigen:
P2X7/P2RX7
Classification:
Monoclonal
Conjugate:
Alexa Fluor 532
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
P2RX7
Immunogen:
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity:
0.1 mL
Gene ID (Entrez):
5027.0
Target Species:
Mouse
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
Hano43
Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias:
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species:
Rat
Purification Method:
Protein G purified
Primary or Secondary:
Primary
Test Specificity:
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage:
Store at 4°C in the dark.
Antigen: P2X7/P2RX7
Classification: Monoclonal
Conjugate: Alexa Fluor 750
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mL
Gene ID (Entrez): 5027.0
Target Species: Mouse
Isotype: IgG2b
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: Hano43
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: Protein G purified
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4°C in the dark.
Antigen:
P2X7/P2RX7
Classification:
Monoclonal
Conjugate:
Alexa Fluor 750
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
P2RX7
Immunogen:
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity:
0.1 mL
Gene ID (Entrez):
5027.0
Target Species:
Mouse
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
Hano43
Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias:
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species:
Rat
Purification Method:
Protein G purified
Primary or Secondary:
Primary
Test Specificity:
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage:
Store at 4°C in the dark.
Antigen: P2X7/P2RX7
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: P2RX7
Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity: 0.1 mL
Gene ID (Entrez): 5027
Target Species: Mouse
Isotype: IgG2b
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: Hano43
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias: ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species: Rat
Purification Method: __
Primary or Secondary: Primary
Test Specificity: This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage: Store at 4°C in the dark.
Antigen:
P2X7/P2RX7
Classification:
Monoclonal
Conjugate:
Alexa Fluor 594
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
P2RX7
Immunogen:
A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Quantity:
0.1 mL
Gene ID (Entrez):
5027
Target Species:
Mouse
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
Hano43
Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias:
ATP receptor, MGC20089, P2X purinoceptor 7, P2X7P2X7 receptor, P2X7R, P2Z receptor, Purinergic receptor, purinergic receptor P2X, ligand-gated ion channel, 7, purinergic receptor P2X7 variant A
Host Species:
Rat
Purification Method:
__
Primary or Secondary:
Primary
Test Specificity:
This antibody recognises the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents.
Content And Storage:
Store at 4°C in the dark.
Antigen: PSMA/FOLH1/NAALADase I
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: FOLH1
Immunogen: amino acids 44-750 of human GCPII
Quantity: 0.1 mL
Gene ID (Entrez): 2346
Target Species: Human
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: GCP-05
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias: Cell growth-inhibiting gene 27 protein, cell growth-inhibiting protein 27, EC 3.4.17.21, folate hydrolase (prostate-specific membrane antigen) 1, Folate hydrolase 1, FOLHNAALADase I, Folylpoly-gamma-glutamate carboxypeptidase, GCP2, GCPIImGCP, glutamate carboxylase II, glutamate carboxypeptidase 2, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, NAALAD1N-acetylated-alpha-linked acidic dipeptidase I, NAALAdase, N-acetylated alpha-linked acidic dipeptidase 1, prostate specific membrane antigen variant F, Prostate-specific membrane antigen, PSMAFGCP, PSMPteroylpoly-gamma-glutamate carboxypeptidase
Host Species: Mouse
Purification Method: __
Primary or Secondary: Primary
Test Specificity: The antibody GCP-05 recognizes extracellular domain of glutamate carboxypeptidase II (NAALADase, FOLH1, PSMA), an approximately 95-110 kDa transmembrane glycoprotein expressed mainly in tumour neovasculatures, nervous system and jejunum, which is an important prostate tumour marker.
Content And Storage: Store at 4°C in the dark.
Antigen:
PSMA/FOLH1/NAALADase I
Classification:
Monoclonal
Conjugate:
Alexa Fluor 350
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
FOLH1
Immunogen:
amino acids 44-750 of human GCPII
Quantity:
0.1 mL
Gene ID (Entrez):
2346
Target Species:
Human
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
GCP-05
Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias:
Cell growth-inhibiting gene 27 protein, cell growth-inhibiting protein 27, EC 3.4.17.21, folate hydrolase (prostate-specific membrane antigen) 1, Folate hydrolase 1, FOLHNAALADase I, Folylpoly-gamma-glutamate carboxypeptidase, GCP2, GCPIImGCP, glutamate carboxylase II, glutamate carboxypeptidase 2, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, NAALAD1N-acetylated-alpha-linked acidic dipeptidase I, NAALAdase, N-acetylated alpha-linked acidic dipeptidase 1, prostate specific membrane antigen variant F, Prostate-specific membrane antigen, PSMAFGCP, PSMPteroylpoly-gamma-glutamate carboxypeptidase
Host Species:
Mouse
Purification Method:
__
Primary or Secondary:
Primary
Test Specificity:
The antibody GCP-05 recognizes extracellular domain of glutamate carboxypeptidase II (NAALADase, FOLH1, PSMA), an approximately 95-110 kDa transmembrane glycoprotein expressed mainly in tumour neovasculatures, nervous system and jejunum, which is an important prostate tumour marker.
Content And Storage:
Store at 4°C in the dark.