NP233060A70

Vimentin Antibody (VM452), Alexa Fluor™ 750, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NP233060A70-Each-of-1 In Stock ₹ 56,298.48

NP233060A70 - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

Vimentin

Classification

Monoclonal

Conjugate

Alexa Fluor 750

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

VIM

Immunogen

Recombinant full-length human vimentin protein (Uniprot: P08670)

Quantity

0.1 mL

Gene ID (Entrez)

7431

Target Species

Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse, Rat

Isotype

IgG1 κ

Applications

Western Blot, ELISA, Immunoassay

Clone

VM452

Dilution

Western Blot, ELISA, Knockout Validated

Gene Alias

FLJ36605, vimentin

Host Species

Mouse

Purification Method

Protein A or G purified

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.

Content And Storage

Store at 4°C in the dark.

Description

  • Vimentin Monoclonal specifically detects Vimentin in Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse (Negative), Rat (Negative) samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin, Knockout Validated.

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Novus Biologicals

NP233060A70

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Antigen:
Vimentin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
VIM

Immunogen:
Recombinant full-length human vimentin protein (Uniprot: P08670)

Quantity:
0.1 mL

Gene ID (Entrez):
7431

Target Species:
Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse, Rat

Isotype:
IgG1 κ

Applications:
Western Blot, ELISA, Immunoassay

Clone:
VM452

Dilution:
Western Blot, ELISA, Knockout Validated

Gene Alias:
FLJ36605, vimentin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP233062A30

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Antigen:
NF-H

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
NEFH

Immunogen:
Triton-X 100 insoluble protein fraction of rat brain (Uniprot: P12036)

Quantity:
0.1 mL

Gene ID (Entrez):
4744.0

Target Species:
Human, Mouse, Rat, Porcine, Chicken

Isotype:
IgG1 κ

Applications:
ELISA

Clone:
RT97

Dilution:
ELISA

Gene Alias:
200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP233062A94

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Antigen:
NF-H

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
NEFH

Immunogen:
Triton-X 100 insoluble protein fraction of rat brain (Uniprot: P12036)

Quantity:
0.1 mL

Gene ID (Entrez):
4744.0

Target Species:
Human, Mouse, Rat, Porcine, Chicken

Isotype:
IgG1 κ

Applications:
ELISA

Clone:
RT97

Dilution:
ELISA

Gene Alias:
200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Content And Storage:
Store at 4°C in the dark.

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Novus Biologicals

NP233064A32

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Antigen:
ErbB2/Her2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
ERBB2

Immunogen:
Recombinant human ErbB2/Her2 protein (Uniprot: IDP04626)

Quantity:
0.1 mL

Gene ID (Entrez):
2064

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
HRB2/451

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Cell Surface)

Gene Alias:
CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.

Content And Storage:
Store at 4°C in the dark.