NP233138A30
Cyclin D1 Antibody (DCS-6), Alexa Fluor™ 350, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NP233138A30-Each-of-1 | In Stock | ₹ 55,271.76 |
NP233138A30 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Cyclin D1
Classification
Monoclonal
Conjugate
Alexa Fluor 350
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
CCND1
Immunogen
Human full length recombinant cyclin D1 protein (Uniprot: P24385)
Quantity
0.1 mL
Gene ID (Entrez)
595
Target Species
Human, Mouse, Rat, Primate
Isotype
IgG2a κ
Applications
ELISA
Clone
DCS-6
Dilution
ELISA
Gene Alias
B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31
Host Species
Mouse
Purification Method
Protein A or G purified
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Content And Storage
Store at 4°C in the dark.
Description
- Cyclin D1 Monoclonal specifically detects Cyclin D1 in Human, Mouse, Rat, Monkey samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: Cyclin D1
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: CCND1
Immunogen: Human full length recombinant cyclin D1 protein (Uniprot: P24385)
Quantity: 0.1 mL
Gene ID (Entrez): 595
Target Species: Human, Mouse, Rat, Primate
Isotype: IgG2a κ
Applications: ELISA
Clone: DCS-6
Dilution: ELISA
Gene Alias: B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31
Host Species: Mouse
Purification Method: Protein A or G purified
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Content And Storage: Store at 4°C in the dark.
Antigen:
Cyclin D1
Classification:
Monoclonal
Conjugate:
Alexa Fluor 350
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
CCND1
Immunogen:
Human full length recombinant cyclin D1 protein (Uniprot: P24385)
Quantity:
0.1 mL
Gene ID (Entrez):
595
Target Species:
Human, Mouse, Rat, Primate
Isotype:
IgG2a κ
Applications:
ELISA
Clone:
DCS-6
Dilution:
ELISA
Gene Alias:
B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31
Host Species:
Mouse
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Content And Storage:
Store at 4°C in the dark.
Antigen: Cyclin D1
Classification: Monoclonal
Conjugate: Alexa Fluor 532
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: CCND1
Immunogen: Human full length recombinant cyclin D1 protein (Uniprot: P24385)
Quantity: 0.1 mL
Gene ID (Entrez): 595
Target Species: Human, Mouse, Rat, Primate
Isotype: IgG2a κ
Applications: ELISA
Clone: DCS-6
Dilution: ELISA
Gene Alias: B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31
Host Species: Mouse
Purification Method: Protein A or G purified
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Content And Storage: Store at 4°C in the dark.
Antigen:
Cyclin D1
Classification:
Monoclonal
Conjugate:
Alexa Fluor 532
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
CCND1
Immunogen:
Human full length recombinant cyclin D1 protein (Uniprot: P24385)
Quantity:
0.1 mL
Gene ID (Entrez):
595
Target Species:
Human, Mouse, Rat, Primate
Isotype:
IgG2a κ
Applications:
ELISA
Clone:
DCS-6
Dilution:
ELISA
Gene Alias:
B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31
Host Species:
Mouse
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Content And Storage:
Store at 4°C in the dark.
Antigen: Cyclin D1
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: CCND1
Immunogen: Human full length recombinant cyclin D1 protein (Uniprot: P24385)
Quantity: 0.1 mL
Gene ID (Entrez): 595
Target Species: Human, Mouse, Rat, Primate
Isotype: IgG2a κ
Applications: ELISA
Clone: DCS-6
Dilution: ELISA
Gene Alias: B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31
Host Species: Mouse
Purification Method: Protein A or G purified
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Content And Storage: Store at 4°C in the dark.
Antigen:
Cyclin D1
Classification:
Monoclonal
Conjugate:
Alexa Fluor 594
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
CCND1
Immunogen:
Human full length recombinant cyclin D1 protein (Uniprot: P24385)
Quantity:
0.1 mL
Gene ID (Entrez):
595
Target Species:
Human, Mouse, Rat, Primate
Isotype:
IgG2a κ
Applications:
ELISA
Clone:
DCS-6
Dilution:
ELISA
Gene Alias:
B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31
Host Species:
Mouse
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Content And Storage:
Store at 4°C in the dark.
Antigen: Kappa Light Chain
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: IGKC
Immunogen: B lymphoma cells
Quantity: 0.1 mL
Gene ID (Entrez): 3514.0
Target Species: Human
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: L1C1
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Host Species: Mouse
Purification Method: Protein A or G purified
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage: Store at 4°C in the dark.
Antigen:
Kappa Light Chain
Classification:
Monoclonal
Conjugate:
Alexa Fluor 350
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
IGKC
Immunogen:
B lymphoma cells
Quantity:
0.1 mL
Gene ID (Entrez):
3514.0
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
L1C1
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Host Species:
Mouse
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage:
Store at 4°C in the dark.