NP23413A94

Bcl-2 Antibody (124), Alexa Fluor™ 594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NP23413A94-Each-of-1 In Stock ₹ 56,298.48

NP23413A94 - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

Bcl-2

Classification

Monoclonal

Conjugate

Alexa Fluor 594

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

BCL2

Immunogen

A synthetic peptide, aa41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein (Uniprot: P10415 )

Quantity

0.1 mL

Gene ID (Entrez)

596

Target Species

Human, Mouse, Rat

Isotype

IgG1 κ

Applications

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

124

Dilution

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias

apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species

Mouse

Purification Method

Protein A or G purified

Primary or Secondary

Primary

Test Specificity

This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage

Store at 4°C in the dark.

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Description

  • Bcl-2 Monoclonal specifically detects Bcl-2 in Human, Mouse (Negative), Rat (Negative) samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NP23413A94

--


Antigen:
Bcl-2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
BCL2

Immunogen:
A synthetic peptide, aa41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein (Uniprot: P10415 )

Quantity:
0.1 mL

Gene ID (Entrez):
596

Target Species:
Human, Mouse, Rat

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
124

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP23416A30

--


Antigen:
EBV Early Antigens

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
__

Immunogen:
Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt′s lymphoma sera

Quantity:
0.1 mL

Gene ID (Entrez):
__

Target Species:
Virus

Isotype:
IgG1 κ

Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
1108-1

Dilution:
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Alias:
Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p63, p73L, TP63, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP23416A32

--


Antigen:
EBV Early Antigens

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
__

Immunogen:
Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt′s lymphoma sera

Quantity:
0.1 mL

Gene ID (Entrez):
__

Target Species:
Virus

Isotype:
IgG1 κ

Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
1108-1

Dilution:
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Alias:
Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p63, p73L, TP63, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP23416A70

--


Antigen:
EBV Early Antigens

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
__

Immunogen:
Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt′s lymphoma sera

Quantity:
0.1 mL

Gene ID (Entrez):
__

Target Species:
Virus

Isotype:
IgG1 κ

Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
1108-1

Dilution:
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Alias:
Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p63, p73L, TP63, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.

Content And Storage:
Store at 4°C in the dark.