NP234663A30

Ku70/XRCC6 Antibody (KU729), Alexa Fluor™ 350, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NP234663A30-Each-of-1 In Stock ₹ 55,271.76

NP234663A30 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Ku70/XRCC6

Classification

Monoclonal

Conjugate

Alexa Fluor 350

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

XRCC6

Immunogen

Nuclear extract of human HL-60 cells

Quantity

0.1 mL

Gene ID (Entrez)

2547

Target Species

Human, Primate, Chicken, Mouse, Rat

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence

Clone

KU729

Dilution

Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)

Gene Alias

5′-deoxyribose-5-phosphate lyase Ku70, 5′-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6

Host Species

Mouse

Purification Method

Protein A or G purified

Primary or Secondary

Primary

Test Specificity

Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Content And Storage

Store at 4°C in the dark.

Description

  • Description Ku70/XRCC6 Monoclonal specifically detects Ku70/XRCC6 in Human, Primate, Chicken (Negative), Mouse (Negative), Rat (Negative) samples
  • It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular).

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Img

Novus Biologicals

NP234663A30

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Antigen:
Ku70/XRCC6

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
XRCC6

Immunogen:
Nuclear extract of human HL-60 cells

Quantity:
0.1 mL

Gene ID (Entrez):
2547

Target Species:
Human, Primate, Chicken, Mouse, Rat

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence

Clone:
KU729

Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)

Gene Alias:
5′-deoxyribose-5-phosphate lyase Ku70, 5′-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP234663A32

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Antigen:
Ku70/XRCC6

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
XRCC6

Immunogen:
Nuclear extract of human HL-60 cells

Quantity:
0.1 mL

Gene ID (Entrez):
2547.0

Target Species:
Human, Primate, Chicken, Mouse, Rat

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence

Clone:
KU729

Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)

Gene Alias:
5′-deoxyribose-5-phosphate lyase Ku70, 5′-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP234664A30

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Antigen:
Lambda Light Chain

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
IGLC1

Immunogen:
Purified human lambda light chain

Quantity:
0.1 mL

Gene ID (Entrez):
3537.0

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
LAM03

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
IGLC, immunoglobulin lambda constant group

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody is specific to Lambda Light Chain of immunoglobulin and shows no cross-reaction with Lambda Light Chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the Lambda Light Chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP234664A70

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Antigen:
Lambda Light Chain

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
IGLC1

Immunogen:
Purified human lambda light chain

Quantity:
0.1 mL

Gene ID (Entrez):
3537.0

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
LAM03

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
IGLC, immunoglobulin lambda constant group

Host Species:
Mouse

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody is specific to Lambda Light Chain of immunoglobulin and shows no cross-reaction with Lambda Light Chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the Lambda Light Chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4°C in the dark.