NP23478A94

CD31/PECAM-1 Antibody (C31.3 + JC/70A), Alexa Fluor™ 594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NP23478A94-Each-of-1 In Stock ₹ 55,271.76

NP23478A94 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

CD31/PECAM-1

Classification

Monoclonal

Conjugate

Alexa Fluor 594

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

PECAM1

Immunogen

Human recombinant CD31/PECAM-1 protein (C31.3) & Membrane preparation of a spleen from a patient with hairy cell leukemia (JC/70A) (Uniprot: P16284)

Quantity

0.1 mL

Gene ID (Entrez)

5175

Target Species

Human, Primate, Rabbit

Isotype

IgG

Applications

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

C31.3 + JC/70A

Dilution

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA′, PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule-1, platelet/endothelial cell adhesion molecule

Host Species

Mouse

Molecular Weight of Antigen

82.5 kDa

Primary or Secondary

Primary

Test Specificity

CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 monoclonal antibody reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Content And Storage

Store at 4°C in the dark.

Description

  • CD31/PECAM-1 Monoclonal specifically detects CD31/PECAM-1 in Human, Primate, Rabbit samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NP23478A94

--


Antigen:
CD31/PECAM-1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PECAM1

Immunogen:
Human recombinant CD31/PECAM-1 protein (C31.3) & Membrane preparation of a spleen from a patient with hairy cell leukemia (JC/70A) (Uniprot: P16284)

Quantity:
0.1 mL

Gene ID (Entrez):
5175

Target Species:
Human, Primate, Rabbit

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
C31.3 + JC/70A

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA′, PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule-1, platelet/endothelial cell adhesion molecule

Host Species:
Mouse

Molecular Weight of Antigen:
82.5 kDa

Primary or Secondary:
Primary

Test Specificity:
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 monoclonal antibody reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP2347A32

--


Antigen:
CD28

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CD28

Immunogen:
Recombinant human CD28 protein (Uniprot: P10747)

Quantity:
0.1 mL

Gene ID (Entrez):
940

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
C28/75

Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
CD28 antigen, CD28 antigen (Tp44), CD28 molecule, MGC138290, T-cell-specific surface glycoprotein CD28, Tp44

Host Species:
Mouse

Molecular Weight of Antigen:
__

Primary or Secondary:
Primary

Test Specificity:
Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP2347A70

--


Antigen:
CD28

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CD28

Immunogen:
Recombinant human CD28 protein (Uniprot: P10747)

Quantity:
0.1 mL

Gene ID (Entrez):
940

Target Species:
Human

Isotype:
IgG1 κ

Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
C28/75

Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
CD28 antigen, CD28 antigen (Tp44), CD28 molecule, MGC138290, T-cell-specific surface glycoprotein CD28, Tp44

Host Species:
Mouse

Molecular Weight of Antigen:
__

Primary or Secondary:
Primary

Test Specificity:
Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

Content And Storage:
Store at 4°C in the dark.

Img

Novus Biologicals

NP23481A30

--


Antigen:
CEACAM5/CD66e

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CEACAM5

Immunogen:
Human colon carcinoma extract (Uniprot: P06731)

Quantity:
0.1 mL

Gene ID (Entrez):
1048

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPM584

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100

Host Species:
Mouse

Molecular Weight of Antigen:
__

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This monoclonal antibody does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbladder, urachus, salivary gland, ovary, and endocervix.

Content And Storage:
Store at 4°C in the dark.