Manufacturer: Novus Biologicals
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NP23488A70-Each-of-1 | In Stock | ₹ 61,560.42 |
NP23488A70 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 61,560.42
GST (18%): ₹ 11,080.876
Total Price: ₹ 72,641.296
CD8
Monoclonal
Alexa Fluor 750
50 mM sodium borate with 0.05% sodium azide
CD8A
A 13 amino acid peptide from C-terminal cytoplasmic domain of alpha chain of human CD8 molecule. (Uniprot: P01732)
0.1 mL
925
Human
IgG1 κ
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
C8/144B
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
CD8, CD8a molecule, LEU2, p32
Mouse
Protein A or G purified
Primary
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Store at 4°C in the dark.