NP24418A70

Integrin beta 3/CD61 Antibody (Y2/51), Alexa Fluor™ 750, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NP24418A70-Each-of-1 In Stock ₹ 55,271.76

NP24418A70 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Integrin beta 3/CD61

Classification

Monoclonal

Conjugate

Alexa Fluor 750

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

ITGB3

Immunogen

Phytohemagglutinin (PHA)-stimulated peripheral blood cells

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

Y2/51

Dilution

Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

CD61, CD61 antigen, GP3Aplatelet glycoprotein IIIa, GPIIIaintegrin beta-3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITG B3, Platelet membrane glycoprotein IIIa

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Angiogenesis, Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Extracellular Matrix, Immunology, Phospho Specific, Signal Transduction, Stem Cell Markers

Gene ID (Entrez)

3690.0

Target Species

Human

Isotype

IgG1 κ

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Description

  • Integrin beta 3/CD61 Monoclonal specifically detects Integrin beta 3/CD61 in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NP24418A70

--


Antigen:
Integrin beta 3/CD61

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
ITGB3

Immunogen:
Phytohemagglutinin (PHA)-stimulated peripheral blood cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
Y2/51

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
CD61, CD61 antigen, GP3Aplatelet glycoprotein IIIa, GPIIIaintegrin beta-3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITG B3, Platelet membrane glycoprotein IIIa

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Angiogenesis, Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Extracellular Matrix, Immunology, Phospho Specific, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
3690.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP24419A30

--


Antigen:
EpCAM/TROP1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
EPCAM

Immunogen:
Recombinant fragment from the extracellular domain of human EpCAM/TROP1 protein (around aa100-224) (exact sequence is proprietary) (Uniprot: P16422 )

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
EGP40/1372

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

Host Species:
Mouse

Purification Method:
__

Research Discipline:
Cancer, Cancer Stem Cells, Tumor Biomarkers

Gene ID (Entrez):
4072

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP24419A70

--


Antigen:
EpCAM/TROP1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
EPCAM

Immunogen:
Recombinant fragment from the extracellular domain of human EpCAM/TROP1 protein (around aa100-224) (exact sequence is proprietary) (Uniprot: P16422 )

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
EGP40/1372

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

Host Species:
Mouse

Purification Method:
__

Research Discipline:
Cancer, Cancer Stem Cells, Tumor Biomarkers

Gene ID (Entrez):
4072

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP2441A30

--


Antigen:
beta-Catenin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CTNNB1

Immunogen:
Recombinant human beta-Catenin protein fragment (Uniprot: P35222)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
CTNNB1/1508

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
beta 1 (88kD), beta-catenin, catenin (cadherin-associated protein), beta 1, 88kDa, catenin beta-1, CTNNB, DKFZp686D02253, FLJ25606, FLJ37923

Host Species:
Mouse

Purification Method:
__

Research Discipline:
__

Gene ID (Entrez):
1499

Target Species:
Human, Mouse, Rat

Isotype:
IgG1 κ