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NP24483A70

RB1 Antibody (1F8), Alexa Fluor™ 750, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NP24483A70-Each-of-1 In Stock ₹ 56,298.48

NP24483A70 - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

RB1

Classification

Monoclonal

Conjugate

Alexa Fluor 750

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

RB1

Immunogen

Recombinant human RB1 protein fragment of 283 amino acid residues. (Uniprot: P06400)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone

1F8

Dilution

Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias

OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Cancer, Cell Cycle and Replication, Phospho Specific, Transcription Factors and Regulators, Tumor Suppressors

Gene ID (Entrez)

5925.0

Target Species

Human, Mouse

Isotype

IgG1 κ

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Description

  • RB1 Monoclonal specifically detects RB1 in Human, Mouse samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Show Difference

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Novus Biologicals

NP24483A70

--

Antigen:
RB1
Classification:
Monoclonal
Conjugate:
Alexa Fluor 750
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
RB1
Immunogen:
Recombinant human RB1 protein fragment of 283 amino acid residues. (Uniprot: P06400)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
1F8
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Cell Cycle and Replication, Phospho Specific, Transcription Factors and Regulators, Tumor Suppressors
Gene ID (Entrez):
5925.0
Target Species:
Human, Mouse
Isotype:
IgG1 κ

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Antigen:
DOG1/TMEM16A
Classification:
Monoclonal
Conjugate:
Alexa Fluor 750
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
ANO1
Immunogen:
Recombinant human canine1/TMEM16A protein fragment (around aa 2-101) (exact sequence is proprietary) (Uniprot: Q5XX6)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
DG1/1486
Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A
Host Species:
Mouse
Purification Method:
__
Research Discipline:
__
Gene ID (Entrez):
55107
Target Species:
Human
Isotype:
IgG2b κ

Img

Novus Biologicals

NP24484A94

--

Antigen:
DOG1/TMEM16A
Classification:
Monoclonal
Conjugate:
Alexa Fluor 594
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
ANO1
Immunogen:
Recombinant human canine1/TMEM16A protein fragment (around aa 2-101) (exact sequence is proprietary) (Uniprot: Q5XX6)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
DG1/1486
Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A
Host Species:
Mouse
Purification Method:
__
Research Discipline:
__
Gene ID (Entrez):
55107
Target Species:
Human
Isotype:
IgG2b κ

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Antigen:
PAX8
Classification:
Monoclonal
Conjugate:
Alexa Fluor 532
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
PAX8
Immunogen:
Recombinant fragment (around aa 60-261) of human PAX8 protein (exact sequence is proprietary) (Uniprot: Q06710)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 62kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
PAX8/1491
Dilution:
Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias:
paired box 8, paired box gene 8, paired box protein Pax-8, paired domain gene 8
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cancer
Gene ID (Entrez):
7849.0
Target Species:
Human
Isotype:
IgG2b κ