NP24770A750

beta 2-Microglobulin Antibody (246-E9.E7 (same as HLA.ABC.m2)), Alexa Fluor™ 750, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NP24770A750-Each-of-1 In Stock ₹ 55,271.76

NP24770A750 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

beta 2-Microglobulin

Classification

Monoclonal

Conjugate

Alexa Fluor 750

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

B2M

Immunogen

Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 12kDa, identified as beta-microglobulin. Beta--microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This monoclonal antibody is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. Detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunofluorescence

Clone

246-E9.E7 (same as HLA.ABC.m2)

Dilution

Flow Cytometry, Immunofluorescence

Gene Alias

beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez)

567.0

Target Species

Human, Primate

Isotype

IgG2a κ

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Description

  • beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate (Negative) samples
  • It is validated for Flow Cytometry, Immunofluorescence.

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Img

Novus Biologicals

NP24770A750

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Antigen:
beta 2-Microglobulin

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
B2M

Immunogen:
Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 12kDa, identified as beta-microglobulin. Beta--microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This monoclonal antibody is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. Detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunofluorescence

Clone:
246-E9.E7 (same as HLA.ABC.m2)

Dilution:
Flow Cytometry, Immunofluorescence

Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez):
567.0

Target Species:
Human, Primate

Isotype:
IgG2a κ

Img

Novus Biologicals

NP24770A94

--


Antigen:
Histone H2B

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
HIST2H2BF

Immunogen:
Ub-polypeptide antigen based on amino acids 115 - 130 of yeast Histone H2B

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, ELISA, Immunocytochemistry, Immunofluorescence

Clone:
1B3F12/A9

Dilution:
Western Blot, ELISA, Immunocytochemistry/Immunofluorescence

Gene Alias:
FLJ35099, FLJ56780, FLJ56787, histone 2, H2bf, histone cluster 2, H2bf, histone H2B type 2-F, MGC131639

Host Species:
Mouse

Purification Method:
Protein A purified

Research Discipline:
Chromatin Research, Epigenetics, Histones and Modified Histones

Gene ID (Entrez):
440689

Target Species:
Human, Yeast

Isotype:
IgG1

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Novus Biologicals

NP247710A30

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Antigen:
SUMO2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
SUMO2

Immunogen:
Recombinant human SUMO2 protein (Uniprot: P55854)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In additi

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SUMO2/1199

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
HSMT3, MGC117191, sentrin 2, Sentrin-2, small ubiquitin-like modifier 2, small ubiquitin-related modifier 2, SMT3 (suppressor of mif two 3, yeast) homolog 2, SMT3 homolog 2, SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae), SMT3 suppressor of mif two 3 homolog 2 (yeast), SMT3A, SMT3B, SMT3H2, SUMO-2, SUMO3, SUMO-3, Ubiquitin-like protein SMT3A, ubiquitin-like protein SMT3B

Host Species:
Mouse

Purification Method:
__

Research Discipline:
Epigenetics

Gene ID (Entrez):
6613

Target Species:
Human, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

NP247710A32

--


Antigen:
SUMO2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
SUMO2

Immunogen:
Recombinant human SUMO2 protein (Uniprot: P55854)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2 and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1, 2 and 3 proteins localize to the nuclear membrane, nuclear bodies and cytoplasm, respectively. SUMO-1 utilizes Ubc9 for conjugation to several target proteins, which include MDM2, p53, PML and RanGap1. SUMO-2 and 3 contribute to a greater percentage of protein modification than does SUMO-1 and unlike SUMO-1, they can form polymeric chains. In additi

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SUMO2/1199

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
HSMT3, MGC117191, sentrin 2, Sentrin-2, small ubiquitin-like modifier 2, small ubiquitin-related modifier 2, SMT3 (suppressor of mif two 3, yeast) homolog 2, SMT3 homolog 2, SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae), SMT3 suppressor of mif two 3 homolog 2 (yeast), SMT3A, SMT3B, SMT3H2, SUMO-2, SUMO3, SUMO-3, Ubiquitin-like protein SMT3A, ubiquitin-like protein SMT3B

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Epigenetics

Gene ID (Entrez):
6613.0

Target Species:
Human, Rat

Isotype:
IgG1 κ