NP24772A30

CD25/IL-2R alpha Antibody (143-13), Alexa Fluor™ 350, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NP24772A30-Each-of-1 In Stock ₹ 55,271.76

NP24772A30 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

CD25/IL-2R alpha

Classification

Monoclonal

Conjugate

Alexa Fluor 350

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

IL2RA

Immunogen

Stimulated human leukocytes

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This monoclonal antibody recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunofluorescence

Clone

143-13

Dilution

Flow Cytometry, Immunofluorescence

Gene Alias

CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR

Host Species

Mouse

Quantity

0.1 mL

Gene ID (Entrez)

3559

Target Species

Human

Isotype

IgG1 κ

Related Products

Img

Novus Biologicals

NP247674A32

--

Img

Novus Biologicals

NP24796A30

--

Img

Novus Biologicals

NP24796A32

--

Img

Novus Biologicals

NP24796A94

--

Img

Novus Biologicals

NP247907A30

--

Img

Novus Biologicals

NP247902A30

--

Img

Novus Biologicals

NP247880A30

--

Img

Novus Biologicals

NP247907A94

--

Description

  • CD25/IL-2R alpha Monoclonal specifically detects CD25/IL-2R alpha in Human samples
  • It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NP24772A30

--


Antigen:
CD25/IL-2R alpha

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
IL2RA

Immunogen:
Stimulated human leukocytes

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkins disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This monoclonal antibody recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunofluorescence

Clone:
143-13

Dilution:
Flow Cytometry, Immunofluorescence

Gene Alias:
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
3559

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP247730A70

--


Antigen:
PTH

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PTH

Immunogen:
A recombinant fragment around aa 32-115 of human mature-PTH-polypeptide (exact sequence is proprietary) (Uniprot: P01270)

Primary or Secondary:
Primary

Test Specificity:
Epitope of this monoclonal antibody maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
PTH/1175

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
5741.0

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NP247731A32

--


Antigen:
PTH

Classification:
Monoclonal

Conjugate:
Alexa Fluor 532

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PTH

Immunogen:
A synthetic peptide around aa 1-34 of human mature-PTH-polypeptide (exact sequence is proprietary) (3H9); A recombinant fragment around aa 32-115 of human mature PTH-polypeptide (exact sequence is proprietary) (Uniprot: P01270)

Primary or Secondary:
Primary

Test Specificity:
Epitope of this monoclonal antibody maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
3H9 + PTH/1175

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
5741.0

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NP247731A70

--


Antigen:
PTH

Classification:
Monoclonal

Conjugate:
Alexa Fluor 750

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PTH

Immunogen:
A synthetic peptide around aa 1-34 of human mature-PTH-polypeptide (exact sequence is proprietary) (3H9); A recombinant fragment around aa 32-115 of human mature PTH-polypeptide (exact sequence is proprietary) (Uniprot: P01270)

Primary or Secondary:
Primary

Test Specificity:
Epitope of this monoclonal antibody maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
3H9 + PTH/1175

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
5741

Target Species:
Human

Isotype:
IgG2b κ