NP247776A94
MCAM/CD146 Antibody (MCAM/1101), Alexa Fluor™ 594, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NP247776A94-Each-of-1 | In Stock | ₹ 55,271.76 |
NP247776A94 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
MCAM/CD146
Classification
Monoclonal
Conjugate
Alexa Fluor 594
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
MCAM
Immunogen
Recombinant human MCAM/CD146 protein (Uniprot: P43121)
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Content And Storage
Store at 4°C in the dark.
Applications
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone
MCAM/1101
Dilution
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias
CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez)
4162.0
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- MCAM/CD146 Monoclonal specifically detects MCAM/CD146 in Human samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.
Compare Similar Items
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Antigen: MCAM/CD146
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: MCAM
Immunogen: Recombinant human MCAM/CD146 protein (Uniprot: P43121)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: MCAM/1101
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez): 4162.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
MCAM/CD146
Classification:
Monoclonal
Conjugate:
Alexa Fluor 594
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
MCAM
Immunogen:
Recombinant human MCAM/CD146 protein (Uniprot: P43121)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
MCAM/1101
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez):
4162.0
Target Species:
Human
Isotype:
IgG1 κ
Antigen: MCAM/CD146
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: MCAM
Immunogen: Recombinant full-length human MCAM/CD146 protein (Uniprot: P43121)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: MUC18/1130
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez): 4162.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
MCAM/CD146
Classification:
Monoclonal
Conjugate:
Alexa Fluor 350
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
MCAM
Immunogen:
Recombinant full-length human MCAM/CD146 protein (Uniprot: P43121)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
MUC18/1130
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez):
4162.0
Target Species:
Human
Isotype:
IgG1 κ
Antigen: MCAM/CD146
Classification: Monoclonal
Conjugate: Alexa Fluor 750
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: MCAM
Immunogen: Recombinant full-length human MCAM/CD146 protein (Uniprot: P43121)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: MUC18/1130
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez): 4162.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
MCAM/CD146
Classification:
Monoclonal
Conjugate:
Alexa Fluor 750
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
MCAM
Immunogen:
Recombinant full-length human MCAM/CD146 protein (Uniprot: P43121)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
MUC18/1130
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez):
4162.0
Target Species:
Human
Isotype:
IgG1 κ
Antigen: B7-2/CD86
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: CD86
Immunogen: Recombinant human full-length B7-2/CD86 protein (Uniprot: P42081)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 70kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin′s disease.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: C86/1146
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence, Knockout Validated
Gene Alias: Activation B7-2 antigen, B70, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Cycle and Replication, Dendritic Cell Markers, Diabetes Research, Immunology, Myeloid derived Suppressor Cell
Gene ID (Entrez): 942.0
Target Species: Human, Mouse, Rat
Isotype: IgG1 κ
Antigen:
B7-2/CD86
Classification:
Monoclonal
Conjugate:
Alexa Fluor 350
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
CD86
Immunogen:
Recombinant human full-length B7-2/CD86 protein (Uniprot: P42081)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 70kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin′s disease.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
C86/1146
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence, Knockout Validated
Gene Alias:
Activation B7-2 antigen, B70, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Cycle and Replication, Dendritic Cell Markers, Diabetes Research, Immunology, Myeloid derived Suppressor Cell
Gene ID (Entrez):
942.0
Target Species:
Human, Mouse, Rat
Isotype:
IgG1 κ