NP247922A94

Pax7 Antibody (PAX7/1187), Alexa Fluor™ 594, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NP247922A94-Each-of-1 In Stock ₹ 57,367.98

NP247922A94 - Each of 1

₹ 57,367.98

In Stock

Quantity

1

Base Price: ₹ 57,367.98

GST (18%): ₹ 10,326.236

Total Price: ₹ 67,694.216

Antigen

Pax7

Classification

Monoclonal

Conjugate

Alexa Fluor 594

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

PAX7

Immunogen

Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Content And Storage

Store at 4°C in the dark.

Applications

Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone

PAX7/1187

Dilution

Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias

FLJ37460, HuP1, paired box 7, paired box gene 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, PAX7 transcriptional factor, PAX7B, RMS2

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Apoptosis, Mesenchymal Stem Cell Markers, Stem Cell Markers

Gene ID (Entrez)

5081.0

Target Species

Human

Isotype

IgG1 κ

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Description

  • Pax7 Monoclonal specifically detects Pax7 in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Novus Biologicals

NP247922A94

--


Antigen:
Pax7

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PAX7

Immunogen:
Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
PAX7/1187

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
FLJ37460, HuP1, paired box 7, paired box gene 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, PAX7 transcriptional factor, PAX7B, RMS2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis, Mesenchymal Stem Cell Markers, Stem Cell Markers

Gene ID (Entrez):
5081.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NP247923A30

--


Antigen:
Pax7

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PAX7

Immunogen:
Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
SPM613

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
FLJ37460, HuP1, paired box 7, paired box gene 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, PAX7 transcriptional factor, PAX7B, RMS2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis, Mesenchymal Stem Cell Markers, Stem Cell Markers

Gene ID (Entrez):
5081.0

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Img

Novus Biologicals

NP247923A94

--


Antigen:
Pax7

Classification:
Monoclonal

Conjugate:
Alexa Fluor 594

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PAX7

Immunogen:
Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
SPM613

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
FLJ37460, HuP1, paired box 7, paired box gene 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, PAX7 transcriptional factor, PAX7B, RMS2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis, Mesenchymal Stem Cell Markers, Stem Cell Markers

Gene ID (Entrez):
5081.0

Target Species:
Human, Mouse

Isotype:
IgG1 κ

Img

Novus Biologicals

NP247926A30

--


Antigen:
Transglutaminase 2/TGM2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
TGM2

Immunogen:
Recombinant full-length human Transglutaminase 2/TGM2 protein (Uniprot: P21980)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a 77-85kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound he

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
TGM2/419

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
C polypeptide, EC 2.3.2.13, G-ALPHA-h, protein-glutamine gamma-glutamyltransferase 2, protein-glutamine-gamma-glutamyltransferase, TG(C), TG2, TGase C, TGase H, TGase-2, TGase-H, TGCGNAH, Tissue transglutaminase, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), Transglutaminase C, Transglutaminase H, Transglutaminase-2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Apoptosis, Immune System Diseases, Immunology, Signal Transduction

Gene ID (Entrez):
7052.0

Target Species:
Human, Mouse, Rat, Monkey, Rabbit

Isotype:
IgG1 κ