Manufacturer: Novus Biologicals
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NP247928A70-Each-of-1 | In Stock | ₹ 55,271.76 |
NP247928A70 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Fucosyltransferase 3/FUT3
Monoclonal
Alexa Fluor 750
50 mM sodium borate with 0.05% sodium azide
Mouse
0.1 mL
2525
Human, Guinea Pig
IgG1 κ
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
SPM194
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
FUT3
Mucin isolated from a human ovarian cyst fluid (Uniprot: P21217)
Primary
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Lewis blood group antigens are carbohydrate moieties structurally integrated in mucous secretions. Lewis antigen system alterations have been described in gastric carcinoma and associated lesions. Anomalous expression of Lewis B antigen has been found in some non-secretory gastric carcinomas and colorectal cancers.
Store at 4°C in the dark.