TFF1/pS2 Antibody (TFF1/1091), Alexa Fluor™ 594, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NP248010A94-Each-of-1 | In Stock | ₹ 53,688.90 |
NP248010A94 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,688.90
GST (18%): ₹ 9,664.002
Total Price: ₹ 63,352.902
Antigen
TFF1/pS2
Classification
Monoclonal
Conjugate
Alexa Fluor 594
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
TFF1
Immunogen
A synthetic peptide from the C-terminus of human TFF1/pS2 protein. (Uniprot: P04155)
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of re
Content And Storage
Store at 4°C in the dark.
Applications
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone
TFF1/1091
Dilution
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias
BCEIbreast cancer, estrogen-inducible sequence expressed in, Breast cancer estrogen-inducible protein, breast cancer estrogen-inducible sequence, D21S21, gastrointestinal trefoil protein pS2, hP1.A, HPS2, pNR-2, Polypeptide P1.A, Protein pS2, pS2, trefoil factor 1, trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancercell line M10HP1.A
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Breast Cancer, Cancer
Gene ID (Entrez)
7031.0
Target Species
Human, Monkey
Isotype
IgG1 κ
Related Products
Description
- TFF1/pS2 Monoclonal specifically detects TFF1/pS2 in Human, Monkey samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: TFF1/pS2
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: TFF1
Immunogen: A synthetic peptide from the C-terminus of human TFF1/pS2 protein. (Uniprot: P04155)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of re
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: TFF1/1091
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: BCEIbreast cancer, estrogen-inducible sequence expressed in, Breast cancer estrogen-inducible protein, breast cancer estrogen-inducible sequence, D21S21, gastrointestinal trefoil protein pS2, hP1.A, HPS2, pNR-2, Polypeptide P1.A, Protein pS2, pS2, trefoil factor 1, trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancercell line M10HP1.A
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Breast Cancer, Cancer
Gene ID (Entrez): 7031.0
Target Species: Human, Monkey
Isotype: IgG1 κ
Antigen: ER alpha/NR3A1
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: ESR1
Immunogen: Recombinant human ER alpha/NR3A1 protein (aa290-560) (Uniprot: P03372)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this monoclonal antibody is mapped between aa300-550. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunofluorescence
Clone: ESR1/420
Dilution: Western Blot, Flow Cytometry, Immunofluorescence
Gene Alias: ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1
Host Species: Mouse
Purification Method: __
Research Discipline: __
Gene ID (Entrez): 2099
Target Species: Human
Isotype: IgG2a κ
Antigen: ER alpha/NR3A1
Classification: Monoclonal
Conjugate: Alexa Fluor 532
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: ESR1
Immunogen: Recombinant human ER alpha/NR3A1 protein (aa290-560) (Uniprot: P03372)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this monoclonal antibody is mapped between aa300-550. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunofluorescence
Clone: ESR1/420
Dilution: Western Blot, Flow Cytometry, Immunofluorescence
Gene Alias: ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1
Host Species: Mouse
Purification Method: __
Research Discipline: __
Gene ID (Entrez): 2099
Target Species: Human
Isotype: IgG2a κ