Antigen:
Clathrin Heavy Chain 1/CHC17
Classification:
Monoclonal
Conjugate:
Alexa Fluor 350
Formulation:
50 mM sodium borate with 0.05% sodium azide
Test Specificity:
Recognizes protein of 192kDa, which is identified as Clathrin Heavy Chain. Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain-binding site. The proximal segment of the Clathrin HC protein is essential for interactions between Clathrin heavy chains and light chains, which result in the formation of the triskelion structure.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Dilution:
Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence
Gene Alias:
CHC, CHC17, clathrin heavy chain 1, Clathrin heavy chain on chromosome 17, clathrin, heavy chain, clathrin, heavy chain (Hc), clathrin, heavy polypeptide (Hc), clathrin, heavy polypeptide-like 2, CLH17, CLH-17, CLTCL2, Hc, KIAA0034
Immunogen:
Purified recombinant N-terminal fragment of human Clathrin Heavy Chain (exact sequence is proprietary)
Primary or Secondary:
Primary