SOX10 Antibody (SOX10/991), Alexa Fluor™ 532, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NP29621A32-Each-of-1 | In Stock | ₹ 58,394.70 |
NP29621A32 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,394.70
GST (18%): ₹ 10,511.046
Total Price: ₹ 68,905.746
Antigen
SOX10
Classification
Monoclonal
Conjugate
Alexa Fluor 532
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
SOX10
Immunogen
Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietary) (Uniprot: P56693)
Primary or Secondary
Primary
Test Specificity
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of ∼55kDa, identified as SOX10. This monoclonal antibody is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately
Content And Storage
Store at 4°C in the dark.
Applications
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
SOX10/991
Dilution
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular)
Gene Alias
MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of
Host Species
Mouse
Quantity
0.1 mL
Gene ID (Entrez)
6663
Target Species
Human, Mouse
Isotype
IgG2b κ
Related Products
Description
- SOX10 Monoclonal specifically detects SOX10 in Human, Mouse samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Intracellular).
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Antigen: SOX10
Classification: Monoclonal
Conjugate: Alexa Fluor 532
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: SOX10
Immunogen: Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietary) (Uniprot: P56693)
Primary or Secondary: Primary
Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of ∼55kDa, identified as SOX10. This monoclonal antibody is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SOX10/991
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Intracellular)
Gene Alias: MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): 6663
Target Species: Human, Mouse
Isotype: IgG2b κ
Antigen: 2A Peptide
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: __
Immunogen: KLH-coupled synthetic peptide corresponding to 2A peptide of Thosea asigna virus (CGDVEENPG)
Primary or Secondary: Primary
Test Specificity: This 2A peptide antibody is specific for T2A and P2A tagged proteins. Specificity to F2A and E2A proteins has not been tested.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Immunocytochemistry, Immunofluorescence
Clone: 3H4
Dilution: Western Blot, Immunocytochemistry/Immunofluorescence
Gene Alias: 2A cleavage peptide, 2A peptide, 2A peptide tag, 2A sequence, Anti- MDV 2A-peptide, anti-2A peptide, anti-2A sequence, anti-2A-like peptide, antibody for 2A-containing recombinant proteins, anti-P2A tagged proteins, anti-P2A peptide, anti-T2A tagged proteins, anti-T2A peptide, anti-Thosea asigna virus 2A, FMDV 2A-peptide, peptide 2A sequences, self-cleaving′2A peptide2a pept, Thosea asigna virus 2A
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): __
Target Species: Non-species specific
Isotype: IgG1 κ
Antigen: 2A Peptide
Classification: Monoclonal
Conjugate: Alexa Fluor 532
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: __
Immunogen: KLH-coupled synthetic peptide corresponding to 2A peptide of Thosea asigna virus (CGDVEENPG)
Primary or Secondary: Primary
Test Specificity: This 2A peptide antibody is specific for T2A and P2A tagged proteins. Specificity to F2A and E2A proteins has not been tested.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Immunocytochemistry, Immunofluorescence
Clone: 3H4
Dilution: Western Blot, Immunocytochemistry/Immunofluorescence
Gene Alias: 2A cleavage peptide, 2A peptide, 2A peptide tag, 2A sequence, Anti- MDV 2A-peptide, anti-2A peptide, anti-2A sequence, anti-2A-like peptide, antibody for 2A-containing recombinant proteins, anti-P2A tagged proteins, anti-P2A peptide, anti-T2A tagged proteins, anti-T2A peptide, anti-Thosea asigna virus 2A, FMDV 2A-peptide, peptide 2A sequences, self-cleaving′2A peptide2a pept, Thosea asigna virus 2A
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): __
Target Species: Non-species specific
Isotype: IgG1 κ