P153GBT50

IL18BP Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 P153GBT50-Each-of-1 In Stock ₹ 24,812.40

P153GBT50 - Each of 1

₹ 24,812.40

In Stock

Quantity

1

Base Price: ₹ 24,812.40

GST (18%): ₹ 4,466.232

Total Price: ₹ 29,278.632

Antigen

IL18BP

Classification

Polyclonal

Conjugate

Biotin

Gene

IL18BP

Gene Alias

Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa

Host Species

Goat

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16068

Content And Storage

-20°C

Applications

ELISA, Western Blot

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q9Z0M9

Gene Symbols

IL18BP

Immunogen

E.coli-derived Recombinant Murine IL-18BP

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Lyophilized

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Description

  • Preparation: Produced from sera of goats immunized with highly pure Recombinant Murine IL-18BP
  • Anti-Murine IL-18BP-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Murine IL-18BP by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine IL-18BP (500-P153G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine IL-18BP
  • Western Blot: To detect mIL-18BP by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant mIL-18BP is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P153GBT-1MG will be provided as 2 x 500 μg Interleukin-18 binding protein (IL-18BP) is a constitutively secreted glycoprotein that acts as a natural antagonist for interleukin-18 (IL-18) by preventing interaction between IL-18 and its receptors
  • Through this binding, IL-18BP neutralizes the proinflammatory role of IL-18 in cell-mediated immune responses, resulting in reduced IFN-gamma production by T helper type I cells and inhibition of allospecific cytotoxic T lymphocyte (CTL) activity through augmented natural killer (NK) cell cytotoxicity
  • As an inhibitor of IL-18 and an essential component of skin homeostasis, IL-18BP has been linked to a variety of diseases, including eczema, asthma, and the autoimmune condition, Crohn's disease
  • The upregulation of IL-18BP by keratinocytes expressing the human papillomavirus (HPV) E7 oncoprotein has been shown to decrease IL-18-induced IFN-gamma production and IL-18-mediated T cell activation
  • Elevated levels of IL-18 and IL-18BP, as well as proinflammatory cytokines IFN-gamma, TNF-alpha, IL-1beta and IL-8, have been linked to chronic inflammation and observed in macrophages (including Kupffer cells) isolated from lesions and intestinal tissues of Crohn's disease patients
  • As a member of the immunoglobulin-like class of receptors, IL-18BP contains a single immunoglobulin (Ig) domain; although two (b and d) of the four identified human isoforms (a-d) contain incomplete domains that greatly reduce their binding affinity.

Compare Similar Items

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Fischer Scientific

P153GBT50

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Antigen:
IL18BP

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IL18BP

Gene Alias:
Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16068

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9Z0M9

Gene Symbols:
IL18BP

Immunogen:
E.coli-derived Recombinant Murine IL-18BP

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Lyophilized

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P154GBT25

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Antigen:
IL-12 p70

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Il12b

Gene Alias:
20C2; CLMF; CLMF p35; CLMF p40; CLMF2; cytokine; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; Cytotoxic lymphocyte maturation factor 40 kDa subunit; il 12; IL 12p70; Il12; IL-12; Il-12 p35; IL-12 p75; IL-12 subunit p35; IL-12 subunit p40; IL-12, subunit p35; IL12, subunit p40; Il-12; cytokine; IL12A; IL-12A; IL12A/B; IL12AB; IL12B; Il-12b; IL12P35; IL-12p35; Il12p40; Il-12p40; IL35 subunit; ILN; IMD28; IMD29; Interleukin; interleukin 12 35 kDa subunit; interleukin 12 35kDa subunit; interleukin 12 40 kDa subunit; interleukin 12 40kDa subunit; interleukin 12 p35 subunit; interleukin 12 p40 subunit precursor; interleukin 12 polypeptide 35; interleukin 12, p35; interleukin 12, p40; interleukin 12A; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin 12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleu

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3592, 3593

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P29459, P29460

Gene Symbols:
IL12A, Il12b

Immunogen:
CHO cells-derived Recombinant Human IL-12 p70

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

Fischer Scientific

P154GBT50

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Antigen:
IL-12 p70

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IL12A

Gene Alias:
20C2; CLMF; CLMF p35; CLMF p40; CLMF2; cytokine; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; Cytotoxic lymphocyte maturation factor 40 kDa subunit; il 12; IL 12p70; Il12; IL-12; Il-12 p35; IL-12 p75; IL-12 subunit p35; IL-12 subunit p40; IL-12, subunit p35; IL12, subunit p40; Il-12; cytokine; IL12A; IL-12A; IL12A/B; IL12AB; IL12B; Il-12b; IL12P35; IL-12p35; Il12p40; Il-12p40; IL35 subunit; ILN; IMD28; IMD29; Interleukin; interleukin 12 35 kDa subunit; interleukin 12 35kDa subunit; interleukin 12 40 kDa subunit; interleukin 12 40kDa subunit; interleukin 12 p35 subunit; interleukin 12 p40 subunit precursor; interleukin 12 polypeptide 35; interleukin 12, p35; interleukin 12, p40; interleukin 12A; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin 12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleu

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3592, 3593

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P29459, P29460

Gene Symbols:
IL12A, Il12b

Immunogen:
CHO cells-derived Recombinant Human IL-12 p70

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

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Sigma Aldrich

P1552

L × W × H 11.4 cm × 8.6 cm × 6.4 cm...


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