PA1072

MINT3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1072-Each-of-1 In Stock ₹ 42,822.78

PA1072 - Each of 1

₹ 42,822.78

In Stock

Quantity

1

Base Price: ₹ 42,822.78

GST (18%): ₹ 7,708.10

Total Price: ₹ 50,530.88

Antigen

MINT3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APBA3

Gene Alias

Adapter protein X11gamma, amyloid beta (A4) precursor protein-binding family A member 3 (X11-like 2), amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2), amyloid beta (A4) precursor protein-binding, family A, member 3, amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2), amyloid beta A4 precursor protein-binding family A member 3, amyloid beta precursor protein binding family A member 3, Amyloid-beta A4 precursor protein-binding family A member 3, Apba3, AW208791, lin 10, lin-10, MGC:15815, Mint 3, MINT3, mint-3, Neuronal Munc18-1-interacting protein 3, neuron-specific X11L2 protein, phosphotyrosine-binding/-interacting domain (PTB)-bearing protein, X11gamma, X11L2, X11-like 2 protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57267, 83611, 9546

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

O70248, O88888, O96018

Gene Symbols

APBA3

Immunogen

Synthetic peptide corresponding to residues M(1) E F L P E P Q H P P G P P T M D L E(19) of rat Mint3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-072 detects munc-18 interacting protein 3 (Mint3) from mouse cells and rat brain samples
  • PA1-072 has been successfully used in Western blot procedures
  • By Western blot, this antibody detects an ∽86 kDa protein representing Mint3 from AtT20 cell extract and rat brain samples
  • The PA1-072 immunogen is a synthetic peptide corresponding to residues M(1) E F L P E P Q H P P G P P T M D L E(19) of rat Mint3
  • The PA1-072 immunizing peptide (Cat
  • # PEP-135) is available for use in neutralization and control experiments
  • The munc-18 interacting protein (Mint) protein family is a group of evolutionarily conserved adaptor proteins that function in membrane transport and organization
  • In mammals, there exist three mint isoforms, Mint1, 2, and 3
  • Although there is little amino acid sequence conservation in the amino-terminal half, the carboxy-terminal half of these proteins is highly conserved
  • Within this conserved portion there exists a phosphotyrosine-binding (PTB) and a PSD-95/DLG-A/ZO-1 (PDZ) domain, which function as protein interaction modules
  • Mint1 and 2 appear to be expressed exclusively in the brain and are found to bind to Munc18, an essential component of the synaptic vesicle fusion machinery
  • Mint3 is ubiquitously expressed in all tissues and is expressed at the lowest levels in the brain and testis
  • Studies show that mint3 does not interact with munc-18
  • Mint3 has been found to interact with the Alzheimer's Disease-related amyloid precursor protein (APP) and does so through its PTB and PDZ domains
  • It has been suggested that mint3 links APP to other transport machinery components, thereby regulating it transport, endocytosis, and metabolism
  • Abnormal APP metabolism has been shown to be the cause of an early-onset type of Alzheimer's disease.

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Thermo Scientific

PA1072

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Antigen:
MINT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APBA3

Gene Alias:
Adapter protein X11gamma, amyloid beta (A4) precursor protein-binding family A member 3 (X11-like 2), amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2), amyloid beta (A4) precursor protein-binding, family A, member 3, amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2), amyloid beta A4 precursor protein-binding family A member 3, amyloid beta precursor protein binding family A member 3, Amyloid-beta A4 precursor protein-binding family A member 3, Apba3, AW208791, lin 10, lin-10, MGC:15815, Mint 3, MINT3, mint-3, Neuronal Munc18-1-interacting protein 3, neuron-specific X11L2 protein, phosphotyrosine-binding/-interacting domain (PTB)-bearing protein, X11gamma, X11L2, X11-like 2 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57267, 83611, 9546

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
O70248, O88888, O96018

Gene Symbols:
APBA3

Immunogen:
Synthetic peptide corresponding to residues M(1) E F L P E P Q H P P G P P T M D L E(19) of rat Mint3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PA1077

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Antigen:
GM130

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Golga2

Gene Alias:
130 kDa cis-Golgi matrix protein; AW555139; cis-Golgi matrix protein GM130; Gm130; GM130 autoantigen; GOLGA2; golgi autoantigen, golgin subfamily a, 2; Golgi matrix protein GM130; golgin A2; Golgin subfamily A member 2; Golgin subfamily A member 2; LOW QUALITY PROTEIN: golgin subfamily A member 2; golgin-95; mKIAA4150; RP11-395P17.5; SY11 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2801

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q08379

Gene Symbols:
Golga2

Immunogen:
Synthetic peptide corresponding to residues G(368) Q V M E S V R Q L Q M E R D K(383) of human GM130.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA1080

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Antigen:
RANBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RANBP1

Gene Alias:
HpaII tiny fragments locus 9A; hpaII tiny fragments locus 9a protein; Htf9a; Htf9-a; Htf9-a/RanBP1; RAN binding protein 1; ran-binding protein 1; RANBP1; RANG; Ran-specific GTPase-activating protein; testis secretory sperm-binding protein Li 221n

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19385, 5902

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P34022, P43487

Gene Symbols:
RANBP1

Immunogen:
Synthetic peptide corresponding to residues M(1) A A A K D T H E D H D T S T E N T(18) C of human RanBP1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA1082

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Antigen:
RANBP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RANBP2

Gene Alias:
358 kDa nucleoporin; A430087B05Rik; acute necrotizing encephalopathy 1 (autosomal dominant); ADANE; AI256741; ANE1; E3 SUMO-protein ligase RanBP2; E3 SUMO-protein transferase RanBP2; IIAE3; Nuclear pore complex protein Nup358; nucleoporin 358; nucleoporin Nup358; NUP358; P270; RAN binding protein 2; ran-binding protein 2; RANBP2; RBP2; retina-specific cyclophilin; RGD1560047; spliced variant with Ran-binding and cyclophilin domains; transformation-related protein 2; TRP1; TRP2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5903, 785768

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P48820, P49792

Gene Symbols:
RANBP2

Immunogen:
Synthetic peptide corresponding to residues M(1) R R S K A D V E R Y I A S V Q G S(18) of human RanBP2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human

Product Type:
Antibody

Isotype:
IgG