PA124894

UCP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA124894-Each-of-1 In Stock ₹ 52,448.28

PA124894 - Each of 1

₹ 52,448.28

In Stock

Quantity

1

Base Price: ₹ 52,448.28

GST (18%): ₹ 9,440.69

Total Price: ₹ 61,888.97

Antigen

UCP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ucp1

Gene Alias

AI385626; HGNC:12517; mitochondrial brown fat uncoupling protein 1; SLC25A7; solute carrier family 25 member 7; Thermogenin; Ucp; UCP 1; Ucp1; Ucpa; uncoupling protein; uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier); uncoupling protein 1, mitochondrial; uncoupling protein, mitochondrial; Uncp; unnamed protein product

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

101089511, 22227, 24860, 7350

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.3 mg/mL

Formulation

0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

P04633, P12242, P25874

Gene Symbols

Ucp1

Immunogen

Synthetic peptide, conjugated to KLH, corresponding to residues 145-159 of human UCP1, with an N-terminal added cysteine.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Feline, Ferret, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-24894 detects UCP1 from human, mouse, and rat samples, and does not cross-react with UCP2 or UCP3
  • PA1-24894 is expected to cross react with bovine (93% conserved), canine (93% conserved), Macaque monkey (100% conserved), rabbit (93% conserved), and ovine (93% conserved) due to sequence homology
  • By Western Blot this antibody detects a band of approximately 32 kDa
  • Positive Control: Brown adipose tissue
  • Mitochondrial uncoupling proteins are members of the family of mitochondrial anion carrier proteins
  • UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak
  • UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane
  • They also reduce the mitochondrial membrane potential in mammalian cells
  • Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known
  • UCPs contain the three homologous protein domains of MACPs
  • This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PA124894

--


Antigen:
UCP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ucp1

Gene Alias:
AI385626; HGNC:12517; mitochondrial brown fat uncoupling protein 1; SLC25A7; solute carrier family 25 member 7; Thermogenin; Ucp; UCP 1; Ucp1; Ucpa; uncoupling protein; uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier); uncoupling protein 1, mitochondrial; uncoupling protein, mitochondrial; Uncp; unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
101089511, 22227, 24860, 7350

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.3 mg/mL

Formulation:
0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P04633, P12242, P25874

Gene Symbols:
Ucp1

Immunogen:
Synthetic peptide, conjugated to KLH, corresponding to residues 145-159 of human UCP1, with an N-terminal added cysteine.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Feline, Ferret, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA124895

--


Antigen:
UCP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ucp3

Gene Alias:
AI645527; mitochondrial uncoupling protein 3; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP3; UCP-3; uncoupling protein; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); uncoupling protein 3, mitochondrial

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22229, 25708, 7352

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.1 mg/mL

Formulation:
0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P55916, P56499, P56501

Gene Symbols:
Ucp3

Immunogen:
Synthetic peptide, conjugated to KLH, corresponding to residues 254-267 of human UCP3 with an N-terminal added lysine.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PA124970

--


Antigen:
GAP43

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GAP43

Gene Alias:
Axonal membrane protein GAP-43; B-50; Basp2; brain abundant, membrane attached signal protein 2; calmodulin-binding protein P-57; Gap43; GAP-43; growth accentuating protein 43; growth associated protein 43; growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; PP46; Protein F1

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
14432, 2596, 29423, 493873

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.02% sodium azide

Gene Accession No.:
P06837, P07936, P17677, Q6S9D9

Gene Symbols:
GAP43

Immunogen:
Purified GAP43 from cat brain.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Feline, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PA125636

--


Antigen:
E. coli serotype O/K

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Escherichia coli

Host Species:
Rabbit

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry

Concentration:
4-5 mg/mL

Formulation:
PBS with 0.1% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Mixtures of all antigenic serotypes.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG