PA14257

RELM alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14257-Each-of-1 In Stock ₹ 44,362.86

PA14257 - Each of 1

₹ 44,362.86

In Stock

Quantity

1

Base Price: ₹ 44,362.86

GST (18%): ₹ 7,985.315

Total Price: ₹ 52,348.175

Antigen

RELM alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Retnla

Gene Alias

1810019L16Rik; cysteine-rich secreted protein A12-gamma; Cysteine-rich secreted protein FIZZ1; Fizz1; Fizz-1; FIZZ2; found in inflammatory zone 1; Himf; HXCP2; Hypoxia-induced mitogenic factor; parasite-induced macrophage novel gene 1 protein; Pmng1; RELMa; RELMalpha; RELM-alpha; RELMb; RELMbeta; RELM-beta; resistin like alpha; resistin-like alpha; Retnla; Xcp2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57262

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q9EP95

Gene Symbols

Retnla

Immunogen

Synthetic peptide corresponding to residues V(31) E N K V K E L L A N P A N(44).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-4257 detects the RELM alpha protein in mouse and human samples
  • PA1-4257 has been successfully used in Western blot procedures
  • By Western blot this antibody detects a ∽15 kDa protein corresponding to secreted mouse RELM alpha from the media of transfected 293T cells
  • The PA1-4257 immunizing peptide corresponds to amino acid residues 31-44 of the mouse RELM alpha protein
  • RELM alpha, also known as Resistin-like alpha or FIZZ1, is a small cytokine (88 aminoacids, MW 9.4 kDa) produced mostly by macrophages
  • Its highest constitutive expression has been observed in small peritoneal macrophages, alveolar macrophages and adipose tissue macrophages
  • It is strongly induced by IL-4 and IL-13
  • Together with Arginase 1 and Ym-1, RELM alpha is considered one of the hallmarks of the M2 polarization of mouse macrophages, however, macrophages polarized with IL-10 (M2c) express neither RELM alpha nor Arginase 1
  • Also, the expression patterns of RELM alpha and Arginase 1 in untreated tissue macrophages significantly differ
  • Elevated levels of RELM alpha may indicate parasitic infection
  • Humans do not have RELM alpha gene but human Resistin resembles mouse RELM alpha in respect to sequence, tissue distribution and function
  • Other members of RELM family in mouse: RELM beta, RELM gamma and Resistin display different tissue distribution and functional properties
  • RELM alpha plays an important role in parasite infection, mucosal inflammation and allergy.

Compare Similar Items

Show Difference

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Thermo Scientific

PA14257

--


Antigen:
RELM alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Retnla

Gene Alias:
1810019L16Rik; cysteine-rich secreted protein A12-gamma; Cysteine-rich secreted protein FIZZ1; Fizz1; Fizz-1; FIZZ2; found in inflammatory zone 1; Himf; HXCP2; Hypoxia-induced mitogenic factor; parasite-induced macrophage novel gene 1 protein; Pmng1; RELMa; RELMalpha; RELM-alpha; RELMb; RELMbeta; RELM-beta; resistin like alpha; resistin-like alpha; Retnla; Xcp2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57262

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9EP95

Gene Symbols:
Retnla

Immunogen:
Synthetic peptide corresponding to residues V(31) E N K V K E L L A N P A N(44).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA14260

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Antigen:
PRAC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRAC1

Gene Alias:
C17orf92; MGC32520; PRAC; PRAC1; prostate cancer susceptibility candidate 1; prostate cancer susceptibility candidate protein 1; Prostate, rectum and colon expressed gene protein; small nuclear protein PRAC; small nuclear protein PRAC1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84366

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q96KF2

Gene Symbols:
PRAC1

Immunogen:
Synthetic peptide: A(4) H F S D Q G P A H L T T S K S(19)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA14261

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Antigen:
TSPYL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSPYL2

Gene Alias:
CASK interacting nucleosome assembly protein; CASK-interacting nucleosome assembly protein; CDA1; Cell division autoantigen 1; cell division autoantigen 1 nucleolar protein; CINAP; CTCL; CTCL tumor antigen se20-4; CTCL-associated antigen se20-4; Cutaneous T-cell lymphoma-associated antigen se20-4; cutaneous T-cell lymphoma-associated tumor antigen se20-4; DENTT; differentially expressed nucleolar TGF-beta1 target; differentially-expressed nucleolar TGF-beta1 target protein; DXBwg1396e; DXHXS1008E; E130307F10Rik; HRIHFB2216; NP79; nuclear protein of 79 kDa; nucleolar TGF-beta1 target protein; RGD1563283; RP1-290F12.2; SE204; testis-specific protein Y encoded-like 2; testis-specific Y-encoded-like protein 2; TSPX; TSPY like 2; Tspyl2; TSPY-like 2; TSPY-like protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64061

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9H2G4

Gene Symbols:
TSPYL2

Immunogen:
Synthetic peptide: N(489) N E T T D N N E S A D D H E(503)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA14266

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Antigen:
XAB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XAB2

Gene Alias:
0610041O14Rik; Adapter protein ATH-55; Ath55; AV025587; crn-related protein kim1; DKFZp762C1015; HCNP; HCNP protein; HCRN; KIAA1177; NTC90; PP3898; Pre-mRNA-splicing factor SYF1; Protein HCNP; SYF1; SYF1 homolog, RNA splicing factor; SYF1 pre-mRNA-splicing factor; Xab2; XPA binding protein 2; XPA-binding protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56949

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9HCS7

Gene Symbols:
XAB2

Immunogen:
Synthetic peptide: E(840) Q Q S V P A A V F G S L K E D(855)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG