PA1601

Endostatin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1601-Each-of-1 In Stock ₹ 48,298.62

PA1601 - Each of 1

₹ 48,298.62

In Stock

Quantity

1

Base Price: ₹ 48,298.62

GST (18%): ₹ 8,693.752

Total Price: ₹ 56,992.372

Antigen

Endostatin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

COL18A1

Gene Alias

antiangiogenic agent; Col18a1; Collagen alpha-1(XVIII) chain; collagen type XVIII alpha 1 chain; collagen, type XVIII, alpha 1; endostatin; FLJ27325; FLJ34914; KNO; KNO1; KS; MGC74745; multi-functional protein MFP; NC1; Non-collagenous domain 1; procollagen, type XVIII, alpha 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12822, 80781

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P39060, P39061

Gene Symbols

COL18A1

Immunogen

Synthetic Peptide: R(129) R L M/T E S Y C E T W R T E(142)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-601 detects recombinant human and mouse endostatin
  • PA1-601 has been successfully used in Western blot, IF/ICC and IHC (P) procedures
  • By Western blot, this antibody detects a 20 kDa protein representing recombinant human endostatin
  • PA1-601 immunizing peptides are two peptides derived from mouse and human endostatin protein corresponding to amino acid residues 129-142 of endostatin
  • PA1-601 can be used with blocking peptide PEP-112
  • Endostatin is able to avoke non-uniform response for proliferation, cell mount and migration of entothelial cells, which different endostatin binding characteristic, leads to the assumption that endostatin effect is strongly dependent from endothelial cell type
  • Furthermore endostatin inhibits angiogenesis and tumor growth in vivo by inducing apoptosis in endothelial cells
  • The local delivery of endostatin seems to specifically affect tumor-associated microvessels by reduction of the vessel density, diameter and functionality
  • Tumor cell migration and invasion was greatly reduced in the endostatin treated animals
  • Endostatin is non-toxic and does not induce aquired drug resistance and has therefor become a potent new therapy strategy in solid neoplasias
  • This therapy appears to have a high potential not only for the treatment of gliomas, the most common brain tumors, but also in other tumors
  • The ability of endostatin to inhibit neoangiogenesis is mediated, at least in part, by Zn^+2 binding and elastase processing
  • Widespread endostatin expression was found in elactic fibers in vessel walls and in some other basement membrane zones
  • Endostatin is released by neurons to accumulate in amyloid plaques in Alzheimer's disease.

Compare Similar Items

Show Difference

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Thermo Scientific

PA1601

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Antigen:
Endostatin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COL18A1

Gene Alias:
antiangiogenic agent; Col18a1; Collagen alpha-1(XVIII) chain; collagen type XVIII alpha 1 chain; collagen, type XVIII, alpha 1; endostatin; FLJ27325; FLJ34914; KNO; KNO1; KS; MGC74745; multi-functional protein MFP; NC1; Non-collagenous domain 1; procollagen, type XVIII, alpha 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12822, 80781

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P39060, P39061

Gene Symbols:
COL18A1

Immunogen:
Synthetic Peptide: R(129) R L M/T E S Y C E T W R T E(142)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA1640

--


Antigen:
KIF2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Kif2a

Gene Alias:
C530030B14Rik; CDCBM3; HK2; hypothetical protein; KIF2; kif2a; kif2-a; kif2a {ECO:0000250; kif2a.L; kinesin family member 2A; kinesin heavy chain family, member 2; kinesin heavy chain member 2; kinesin heavy chain member 2A; kinesin heavy chain member 2A L homeolog; Kinesin, heavy chain, 2; kinesin-2; Kinesin-like protein KIF2A; kinesin-related protein XKIF2; Kns2; M-kinesin; RCJMB04_9a7; UniProtKB:O00139}; Unknown (protein for MGC:133806); XELAEV_18008243mg

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16563

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P28740

Gene Symbols:
Kif2a

Immunogen:
Synthetic Peptide: M(1) V T S L N E D N E S(11) C

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PA1654A

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Antigen:
LAMP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LAMP1

Gene Alias:
120 kDa lysosomal membrane glycoprotein; AI196048; CD107 antigen-like family member A; CD107a; I79_011073; Lamp I; LAMP1; LAMP-1; LAMPA; LGP120; LGP-120; LGPA; LGP-A; lysosomal associated membrane protein 1; Lysosomal associated membrane protein 1 (120 kDa); lysosomal membrane glycoprotein 1; lysosomal membrane glycoprotein A; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 1 PRECURSOR (LAMP-1) (LGP-A) (LGP-120) (CD107A) (P2B); lysosome-associated membrane protein 1; P2B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3916

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide; pH 7.4

Gene Accession No.:
P11279

Gene Symbols:
LAMP1

Immunogen:
Synthetic peptide corresponding to residues C K(407) R S H A G Y Q T I(416) of human LAMP1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA1655

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Antigen:
LAMP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LAMP2

Gene Alias:
CD107 antigen-like family member B; CD107b; EGK_20887; Igp96; Lamp II; LAMP2; LAMP-2; LAMP-2 Isoform 2A; LAMP-2 Variant A; Lamp-2a; Lamp-2b; Lamp-2c; LAMPB; LGP110; LGP-110; LGP-96; LGP-B; lysosomal associated membrane protein 2; lysosomal membrane glycoprotein 2; lysosomal membrane glycoprotein type B; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; lysosome-associated membrane protein 2; Mac3; RP23-193O17.2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16784, 24944, 3920

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P13473, P17046, P17047

Gene Symbols:
LAMP2

Immunogen:
Synthetic Peptide: C G(400) L K R H H T G Y E Q F(411)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG