PA1774

RPH3A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1774-Each-of-1 In Stock ₹ 45,902.94

PA1774 - Each of 1

₹ 45,902.94

In Stock

Quantity

1

Base Price: ₹ 45,902.94

GST (18%): ₹ 8,262.529

Total Price: ₹ 54,165.469

Antigen

RPH3A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RPH3A

Gene Alias

2900002P20Rik; AU022689; AW108370; Exophilin 1; Exophilin1; Exophilin-1; KIAA0985; rabphilin 3A; rabphilin 3A homolog; rabphilin-3A; RPH3A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

171039, 19894

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P47708, P47709

Gene Symbols

RPH3A

Immunogen

Synthetic peptide corresponding to residues M(1) T D T V V N R W M Y P G D G P L Q(18) C of rat Rabphilin 3A.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-774 detects rabphilin 3A from rat tissues
  • PA1-774 has been successfully used in Western blot procedures
  • By Western blot, this antibody detects an ∽75 kDa protein representing rabphilin 3A from rat brain whole protein extract
  • PA1-774 immunogen is a synthetic peptide corresponding to residues M(1) T D T V V N R W M Y P G D G P L Q(18) C of rat Rabphilin 3A
  • This sequence is completely conserved between rat and mouse rabphilin 3A
  • PA1-774 immunizing peptide (Cat
  • # PEP-102) is available for use in neutralization and control experiments
  • The carboxy-terminal of rabphilin-3A consists of two C2 domains, A and B, and the amino-terminal (residues 45-170) contains a cysteine-rich rich region with two zinc finger motifs
  • Rabphilin-3A belongs to a family of other carboxyterminal type (C-type) tandem C2 proteins, which includes synaptotagmins and Doc2
  • Rabphilin is expressed in neuroendocrine cells and co-localizes with Rab3A on synaptic vesicles and chromaffin granules
  • Rabphilin-3A binds Rab3a/GTP/Mg+ within amino-terminal residues 45 and 170
  • Rabphilin-3A binds calcium ions and phosphatidylinositol 4,5-bisphophate containing lipid vesicles within its C2 domains
  • Rabphilin-3A is a positive regulator of calcium dependent exocytosis, while Rab3a is a negative regulator of exocytosis
  • Although rabphilin-3A associates with Rab3a, they seem to influence exocytosis independently of each other
  • Rabphilin-3A effects are likely mediated through interactions with an unknown factor that recognizes the Rab3 binding domain.

Compare Similar Items

Show Difference

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Thermo Scientific

PA1774

--


Antigen:
RPH3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPH3A

Gene Alias:
2900002P20Rik; AU022689; AW108370; Exophilin 1; Exophilin1; Exophilin-1; KIAA0985; rabphilin 3A; rabphilin 3A homolog; rabphilin-3A; RPH3A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171039, 19894

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P47708, P47709

Gene Symbols:
RPH3A

Immunogen:
Synthetic peptide corresponding to residues M(1) T D T V V N R W M Y P G D G P L Q(18) C of rat Rabphilin 3A.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA1775

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Antigen:
RAB11B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rab11b

Gene Alias:
A730055L17Rik; GTP-binding protein YPT3; H-YPT3; RAB11B; RAB11B, member of RAS oncogene family; RAB11B, member RAS oncogene family; RAS oncogene family protein; ras-related protein Rab-11B; YPT3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
611619, 9230

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q15907

Gene Symbols:
Rab11b

Immunogen:
Synthetic peptide corresponding to residues M(1) G T R D D E Y D Y L F K V V L I C(17) of human Rab11.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

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PA1801

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Antigen:
PAX6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PAX6

Gene Alias:
1500038E17Rik; AEY11; AN; AN2; Aniridia; aniridia type II protein; D11S812E; Dey; Dickie's small eye; FVH1; Gsfaey11; Keratitis; MGC17209; MGDA; oculorhombin; paired box 6; paired box gene 6; Paired Box Gene-6; paired box homeotic gene 6; paired box homeotic gene-6; paired box protein Pax-6; Pax6; Pax-6; PAX6 protein; Sey; small eye; transcription factor; WAGR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18508, 25509, 5080, 554264

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P26367, P63015, P63016

Gene Symbols:
PAX6

Immunogen:
Synthetic peptide corresponding to residues C R(267) E E K L R N Q R R Q A S N T P S H I(285) of mouse PAX6.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Ovine, Rat

Product Type:
Antibody

Isotype:
IgG

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PA1802

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Antigen:
FOXL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXL2

Gene Alias:
AU045128; Blepharophimosis; BPES; BPES1; epicanthus inversus; forkhead box L2; forkhead box protein L2; forkhead transcription factor; forkhead transcription factor FOXL2; forkhead transcription factor L2; Foxl2; LUSTR2; MGC14393; Pfrk; P-Frk; PINTO; pituitary forkhead factor; POF3; putative transcription factor foxl2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26927, 668

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
O88470, P58012

Gene Symbols:
FOXL2

Immunogen:
Synthetic Peptide corresponding to residues M(1) M A S Y P E P E D T A G T(14) of mouse FoxL2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse

Product Type:
Antibody

Isotype:
IgG