PA1888

MECP2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA1888-Each-of-1 In Stock ₹ 48,213.06

PA1888 - Each of 1

₹ 48,213.06

In Stock

Quantity

1

Base Price: ₹ 48,213.06

GST (18%): ₹ 8,678.351

Total Price: ₹ 56,891.411

Antigen

MECP2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mecp2

Gene Alias

1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17257, 29386, 4204

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P51608, Q00566, Q9Z2D6

Gene Symbols

Mecp2

Immunogen

Synthetic Peptide: C P(469) N R E E P V D S R T P V T E R V S(486)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-888 detects methyl CpG binding protein 2 (MeCP2) from human, mouse and rat cells and tissues
  • PA1-888 has been successfully used in Western blot procedures
  • By Western blot, this antibody detects an ∽56 kDa protein representing MeCP2 from AtT20 cell extract
  • PA1-888 immunizing peptide corresponds to amino acid residues 469-486 from human MeCP2
  • This sequence is completely conserved in rat and mouse MeCP2
  • PA1-888 immunizing peptide (Cat
  • # PEP-121) is available for use in neutralization and control experiments
  • MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain
  • MECP2 is capable of binding specifically to methylated DNA
  • DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
  • MECP2 can also repress transcription from methylated gene promoters
  • In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation
  • MECP2 is dispensible in stem cells, but is essential for embryonic development
  • MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PA1888

--


Antigen:
MECP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mecp2

Gene Alias:
1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17257, 29386, 4204

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P51608, Q00566, Q9Z2D6

Gene Symbols:
Mecp2

Immunogen:
Synthetic Peptide: C P(469) N R E E P V D S R T P V T E R V S(486)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PA1889

--


Antigen:
MBD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MBD1

Gene Alias:
CXXC3; CXXC-type zinc finger protein 3; Mbd1; methyl-CpG binding domain protein 1; methyl-CpG binding domain protein 1 isoform PCM1; methyl-CpG-binding domain protein 1; Methyl-CpG-binding protein MBD1; PCM1; Protein containing methyl-CpG-binding domain 1; RFT; the regulator of fibroblast growth factor 2 (FGF-2) transcription

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4152

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q9UIS9

Gene Symbols:
MBD1

Immunogen:
Synthetic Peptide: C R(593) S K D L K K P G A R K Q(605)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA1901

--


Antigen:
IP3 Receptor 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Itpr1

Gene Alias:
ACV; CLA4; D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 1,4,5-trisphosphate receptor, type 1; inositol 1,4,5-trisphosphate-binding protein P400; InsP>3<R type I; Insp3r; InsP3R type I; insP3R1; IP3 receptor; IP3 receptor isoform 1; Ip3r; IP-3-R; IP3R 1; IP3R1; Itpr1; Itpr-1; opisthotonus; opt; P400; Pcd6; Pcp1; Pcp-1; PPP1R94; protein PCD-6; protein phosphatase 1, regulatory subunit 94; Purkinje cell protein 1; SCA15; SCA16; SCA29; SI-SIII-SIIA; Type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16438, 25262, 3708, 476548

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration:
1.3 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P11881, P29994, Q14643

Gene Symbols:
Itpr1

Immunogen:
Synthetic Peptide: N(1829) K K K D D E V D R D A P S R K K A K E(1848)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PA1902A

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Antigen:
Calreticulin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CALR

Gene Alias:
Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA

Host Species:
Chicken

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100689096, 12317, 476694, 64202, 811

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.1 mg/mL

Formulation:
antibody with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P14211, P18418, P27797, P28490, Q8K3H7

Gene Symbols:
CALR

Immunogen:
Synthetic Peptide: K(24) E Q F L D G D A W T N R W V E S K H K(43).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Hamster, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgY