PA1924

KCNMB1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1924-Each-of-1 In Stock ₹ 47,785.26

PA1924 - Each of 1

₹ 47,785.26

In Stock

Quantity

1

Base Price: ₹ 47,785.26

GST (18%): ₹ 8,601.347

Total Price: ₹ 56,386.607

Antigen

KCNMB1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KCNMB1

Gene Alias

big potassium channel beta subunit 1; BK channel beta subunit; BK channel beta subunit 1; BK channel subunit beta-1; BKbeta; BKbeta1; calcium-activated potassium channel beta subunit; calcium-activated potassium channel subunit beta; Calcium-activated potassium channel subunit beta-1; calcium-activated potassium channel, subfamily M subunit beta-1; Charybdotoxin receptor subunit beta-1; hbeta1; hslo-beta; K(VCA)beta; k(VCA)beta-1; Kcnmb1; large conductance Ca2+-activated K+ channel beta 1 subunit; maxi K channel subunit beta-1; MaxiK channel beta-subunit 1; potassium calcium-activated channel subfamily M regulatory beta subunit 1; potassium channel subfamily M regulatory beta subunit 1; potassium large conductance calcium-activated channel, subfamily M, beta member 1; slo-beta; slo-beta-1; slowpoke-beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16533, 29747, 3779

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P97678, Q16558, Q8CAE3

Gene Symbols

KCNMB1

Immunogen

Synthetic Peptide: L(90) Y H T E D T R D Q N Q Q C(103)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-924 detects large conductance, calcium-activated potassium channel beta (Maxi K+ Beta) from human, mouse, and rat samples
  • PA1-924 has been successfully used in western blot and immunofluorescence
  • By western blot, this antibody detects an ∽28kDa protein representing Maxi K+ beta from mouse myometrial smooth muscle cell extracts
  • The molecular weight detected varies due to glycosylation, multimerization and binding to actin
  • Immunizing peptide corresponds to amino acid residues 90-103 from human Maxi K+ beta
  • This sequence is completely conserved across many species
  • PA1-924 immunizing peptide (Cat
  • # PEP-119) is available for use in neutralization and control experiments
  • Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells
  • One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+)
  • Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization
  • Maxi K+ dual activation is possible because of its structure
  • The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain
  • In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry
  • The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open
  • Maxi K+ beta is the target for possible therapeutics because of its role in blood flow and blood pressure regulation.

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PA1924

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Antigen:
KCNMB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNMB1

Gene Alias:
big potassium channel beta subunit 1; BK channel beta subunit; BK channel beta subunit 1; BK channel subunit beta-1; BKbeta; BKbeta1; calcium-activated potassium channel beta subunit; calcium-activated potassium channel subunit beta; Calcium-activated potassium channel subunit beta-1; calcium-activated potassium channel, subfamily M subunit beta-1; Charybdotoxin receptor subunit beta-1; hbeta1; hslo-beta; K(VCA)beta; k(VCA)beta-1; Kcnmb1; large conductance Ca2+-activated K+ channel beta 1 subunit; maxi K channel subunit beta-1; MaxiK channel beta-subunit 1; potassium calcium-activated channel subfamily M regulatory beta subunit 1; potassium channel subfamily M regulatory beta subunit 1; potassium large conductance calcium-activated channel, subfamily M, beta member 1; slo-beta; slo-beta-1; slowpoke-beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16533, 29747, 3779

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P97678, Q16558, Q8CAE3

Gene Symbols:
KCNMB1

Immunogen:
Synthetic Peptide: L(90) Y H T E D T R D Q N Q Q C(103)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA1929

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Antigen:
KCNQ2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNQ2

Gene Alias:
BFNC; EBN; EBN1; ENB1; HNSPC; KCNA11; KCNQ2; KQT like 2; KQT2; KQT-like 2; KV7.2; KVEBN1; mKQT2.3; mKQT2.4; neuroblastoma-specific potassium channel subunit alpha KvLQT2; Nmf134; potassium channel subunit alpha KvLQT2; potassium channel, voltage gated KQT-like subfamily Q, member 2; potassium channel, voltage-gated KQT-like subfamily Q, member 2; potassium voltage-gated channel KQT-like subfamily member 2.3; potassium voltage-gated channel KQT-like subfamily member 2.4; potassium voltage-gated channel subfamily KQT member 2; potassium voltage-gated channel subfamily Q member 2; potassium voltage-gated channel, KQT-like subfamily, member 2; potassium voltage-gated channel, subfamily Q, member 2; voltage-gated potassium channel subunit Kv7.2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16536, 170848, 3785

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
O43526, O88943, Q9Z351

Gene Symbols:
KCNQ2

Immunogen:
GST fusion protein encoding the first 70 amino acids of human KCNQ2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA1930

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Antigen:
KCNQ3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNQ3

Gene Alias:
BFNC; BFNC2; EBN2; Kcnq3; KQT-like 3; KV7.3; potassium channel subunit alpha KvLQT3; potassium channel, voltage gated KQT-like subfamily Q, member 3; potassium channel, voltage-gated KQT-like subfamily Q, member 3; potassium channel, voltage-gated, subfamily Q, member 3; potassium voltage-gated channel subfamily KQT member 3; potassium voltage-gated channel subfamily Q member 3; potassium voltage-gated channel, KQT-like subfamily, member 3; potassium voltage-gated channel, subfamily Q, member 3; voltage-gated potassium channel subunit Kv7.3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110862, 29682, 3786

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen)

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.02% sodium azide

Gene Accession No.:
O43525, O88944, Q8K3F6

Gene Symbols:
KCNQ3

Immunogen:
GST fusion protein encoding the first 71 amino acids of rat KCNQ3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA1932

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Antigen:
S100A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
S100A1

Gene Alias:
AI266795; Protein S100-A1; S100; S100 alpha; S100 calcium binding protein A1; S100 calcium-binding protein A1; S-100 protein alpha chain; S-100 protein subunit alpha; S100 protein, alpha polypeptide; S100a; S100A1; S100-alpha

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
106504218, 20193, 295214, 528735, 6271

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20mg/mL BSA and 0.1% sodium azide

Gene Accession No.:
P02639, P23297, P35467, P56565

Gene Symbols:
S100A1

Immunogen:
Purified S100-alpha protein from human pectoral muscle cells.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG