PA540129

SHARPIN Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA540129-Each-of-1 In Stock ₹ 44,705.10

PA540129 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SHARPIN

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SHARPIN

Gene Alias

0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

81858

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

3.41 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

Q9H0F6

Gene Symbols

SHARPIN

Immunogen

Recombinant protein encompassing a sequence within the center region of human SHARPIN.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: K562 and THP-1 cells
  • Predicted reactivity: Chimpanzee (96%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation
  • LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways
  • Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation
  • LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex
  • Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.

Compare Similar Items

Show Difference

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Thermo Scientific

PA540129

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Antigen:
SHARPIN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SHARPIN

Gene Alias:
0610041B22Rik; AW121341; Conneck1; cpdm; hSIPL1; mSIPL1; protein kinase C-interacting protein RBCC like 1; PSEC0216; RBCKL1; SHANK associated RH domain interactor; SHANK-associated RH domain interacting protein; SHANK-associated RH domain interactor; shank-associated RH domain-interacting protein; shank-interacting protein; shank-interacting protein-like 1; SHARPIN; SIPL1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
81858

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
3.41 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q9H0F6

Gene Symbols:
SHARPIN

Immunogen:
Recombinant protein encompassing a sequence within the center region of human SHARPIN.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA540130

--


Antigen:
STAG2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAG2

Gene Alias:
9230105L23Rik; B230112I07Rik; bA517O1.1; cohesin subunit SA-2; DKFZp686P168; DKFZp781H1753; FLJ25871; nuclear protein SA2; OTTHUMP00000024338; OTTHUMP00000043514; OTTHUMP00000043515; OTTHUMP00000081754; OTTHUMP00000081755; RGD1562042; RP11-517O1.1; SA2; SA-2; Sap2; SCC3 homolog 2; SCC3B; STAG2; Stromal antigen 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10735

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
0.15 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q8N3U4

Gene Symbols:
STAG2

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human STAG2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA540131

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Antigen:
Ataxin 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atxn2

Gene Alias:
9630045M23Rik; ASL13; ataxin 2; ataxin-2; ATX2; Atxn2; AW544490; FLJ46772; SCA2; spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2); spinocerebellar ataxia 2 homolog; spinocerebellar ataxia type 2 protein; Spinocerebellar ataxia type 2 protein homolog; TNRC13; Trinucleotide repeat-containing gene 13 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20239, 6311

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.28 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O70305, Q99700

Gene Symbols:
Atxn2

Immunogen:
Recombinant protein within aa 604-796 of human ATXN2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA540132

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Antigen:
TDRD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tdrd1

Gene Alias:
Cancer/testis antigen 41.1; CT41.1; FLJ21082; MTR-1; Tdrd1; testicular tissue protein Li 193; tudor domain containing 1; tudor domain containing protein 1; tudor domain-containing protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56165

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.32 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q9BXT4

Gene Symbols:
Tdrd1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human TDRD1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG