PA540270
Phospho-MER/SKY (Tyr749, Tyr681) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA540270-Each-of-1 | In Stock | ₹ 45,132.90 |
PA540270 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,132.90
GST (18%): ₹ 8,123.922
Total Price: ₹ 53,256.822
Antigen
Phospho-MER/SKY (Tyr749, Tyr681)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MERTK
Gene Alias
AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Dtk; EC 2.7.10.2; Etk-2; etk2/tyro3; Eyk; kinase Syk; KSYK; Mer; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; Receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; Rek; retinal dystrophy; RP38; RSE; Sky; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; SYK; Tif; TK19-2; Tyro 12; Tyro12; Tyro3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; tyrosine-protein kinase Mer; Tyrosine-protein kinase receptor TYRO3; tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; tyrosine-protein kinase TIF
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10461, 17289, 22174, 25232, 65037, 7301
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA, Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P55144, P55146, P57097, Q06418, Q12866, Q60805
Gene Symbols
MERTK, TYRO3
Immunogen
Synthesized peptide derived from human MerTK/Tyro3 around the phosphorylation site of Y749/681.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with mouse and rat based on sequence homology
- Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6
- Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
- Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
- Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
- MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
- Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
- Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
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Antigen: Phospho-MER/SKY (Tyr749, Tyr681)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MERTK
Gene Alias: AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Dtk; EC 2.7.10.2; Etk-2; etk2/tyro3; Eyk; kinase Syk; KSYK; Mer; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; Receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; Rek; retinal dystrophy; RP38; RSE; Sky; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; SYK; Tif; TK19-2; Tyro 12; Tyro12; Tyro3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; tyrosine-protein kinase Mer; Tyrosine-protein kinase receptor TYRO3; tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; tyrosine-protein kinase TIF
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10461, 17289, 22174, 25232, 65037, 7301
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P55144, P55146, P57097, Q06418, Q12866, Q60805
Gene Symbols: MERTK, TYRO3
Immunogen: Synthesized peptide derived from human MerTK/Tyro3 around the phosphorylation site of Y749/681.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MER/SKY (Tyr749, Tyr681)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MERTK
Gene Alias:
AI323366; Brt; Bruton agammaglobulinemia tyrosine kinase; BYK; c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Dtk; EC 2.7.10.2; Etk-2; etk2/tyro3; Eyk; kinase Syk; KSYK; Mer; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; Receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; Rek; retinal dystrophy; RP38; RSE; Sky; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; SYK; Tif; TK19-2; Tyro 12; Tyro12; Tyro3; TYRO3 protein tyrosine kinase; TYRO3 protein tyrosine kinase 3; tyrosine-protein kinase byk; Tyrosine-protein kinase DTK; tyrosine-protein kinase Mer; Tyrosine-protein kinase receptor TYRO3; tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; tyrosine-protein kinase TIF
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10461, 17289, 22174, 25232, 65037, 7301
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P55144, P55146, P57097, Q06418, Q12866, Q60805
Gene Symbols:
MERTK, TYRO3
Immunogen:
Synthesized peptide derived from human MerTK/Tyro3 around the phosphorylation site of Y749/681.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-TOP2A (Ser1525)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TOP2A
Gene Alias: DNA gyrase; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase 2-alpha; DNA topoisomerase 2-alpha-like protein; DNA Topoisomerase II alpha; DNA topoisomerase II, 170 kD; DNA topoisomerase II, alpha isozyme; EC 5.99.1.3; OTTHUMP00000207108; P11388-1; TOP2; Top-2; Top2a; TOPOII; topoisomerase (DNA) 2 alpha; topoisomerase (DNA) II alpha; topoisomerase (DNA) II alpha 170kDa; topoisomerase ii alpha; topoisomersae II; TP2A
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21973, 360243, 7153
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P11388, P41516, Q01320
Gene Symbols: TOP2A
Immunogen: Synthesized peptide derived from human Topo IIalpha around the phosphorylation site of S1525.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TOP2A (Ser1525)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TOP2A
Gene Alias:
DNA gyrase; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase 2-alpha; DNA topoisomerase 2-alpha-like protein; DNA Topoisomerase II alpha; DNA topoisomerase II, 170 kD; DNA topoisomerase II, alpha isozyme; EC 5.99.1.3; OTTHUMP00000207108; P11388-1; TOP2; Top-2; Top2a; TOPOII; topoisomerase (DNA) 2 alpha; topoisomerase (DNA) II alpha; topoisomerase (DNA) II alpha 170kDa; topoisomerase ii alpha; topoisomersae II; TP2A
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21973, 360243, 7153
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P11388, P41516, Q01320
Gene Symbols:
TOP2A
Immunogen:
Synthesized peptide derived from human Topo IIalpha around the phosphorylation site of S1525.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-JNK1/JNK2/JNK3 (Tyr185)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAPK8
Gene Alias: AI849689; AI851083; C230008H04Rik; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; hypothetical protein LOC569698; janus kinase 1; janus kinase 2; JNK; JNK 46; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; Jnk2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; Jnk3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAP kinase p49 3F12; MAPK 10; MAPK 8; MAPK 9; Mapk10; Mapk8; Mapk9; MGC137545 protein; MGC50974; Mi; mitogen activated protein kinase 10; mitogen activated protein kinase 8; mitogen activated protein kinase 9; mitogen-activated protein kinase 10; Mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 9; MK10; p493F12; p54 gamma; p54a; p54-alpha; p54aSAPK; p54-beta; p54bSAPK; Phospho-JNK; PRKM10; Prkm8; PRKM9; protein kinase mitogen-activated 8; protein kinase, mitogen-activated 9; SAPb; SAPK; SAPK gamma; SAPK(beta); SAPK/Erk/kinase 2; SAPK1; SAPK1a; SAPK1B; SAPK1c; SAPK-alpha; SAPK-beta; SAPKC; Serk2; si:ch211-247j9.2; stress activated protein kinase alpha II; Stress activated protein kinase beta; stress-activated protein kinase 1; stress-activated protein kinase 1a; Stress-activated protein kinase 1b; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; stress-activated protein kinase JNK2; Stress-activated protein kinase JNK3; zgc:123234
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P45983, P45984, P49185, P49186, P49187, P53779, Q61831, Q91Y86, Q9WTU6
Gene Symbols: MAPK10, MAPK8, MAPK9
Immunogen: Synthesized peptide derived from human JNK1/2/3 around the phosphorylation site of Y185.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-JNK1/JNK2/JNK3 (Tyr185)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAPK8
Gene Alias:
AI849689; AI851083; C230008H04Rik; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; hypothetical protein LOC569698; janus kinase 1; janus kinase 2; JNK; JNK 46; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; Jnk2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; Jnk3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAP kinase p49 3F12; MAPK 10; MAPK 8; MAPK 9; Mapk10; Mapk8; Mapk9; MGC137545 protein; MGC50974; Mi; mitogen activated protein kinase 10; mitogen activated protein kinase 8; mitogen activated protein kinase 9; mitogen-activated protein kinase 10; Mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 9; MK10; p493F12; p54 gamma; p54a; p54-alpha; p54aSAPK; p54-beta; p54bSAPK; Phospho-JNK; PRKM10; Prkm8; PRKM9; protein kinase mitogen-activated 8; protein kinase, mitogen-activated 9; SAPb; SAPK; SAPK gamma; SAPK(beta); SAPK/Erk/kinase 2; SAPK1; SAPK1a; SAPK1B; SAPK1c; SAPK-alpha; SAPK-beta; SAPKC; Serk2; si:ch211-247j9.2; stress activated protein kinase alpha II; Stress activated protein kinase beta; stress-activated protein kinase 1; stress-activated protein kinase 1a; Stress-activated protein kinase 1b; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; stress-activated protein kinase JNK2; Stress-activated protein kinase JNK3; zgc:123234
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P45983, P45984, P49185, P49186, P49187, P53779, Q61831, Q91Y86, Q9WTU6
Gene Symbols:
MAPK10, MAPK8, MAPK9
Immunogen:
Synthesized peptide derived from human JNK1/2/3 around the phosphorylation site of Y185.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-CrkL (Tyr207)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CRKL
Gene Alias: 1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12929, 1399, 287942
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P46109, P47941, Q5U2U2
Gene Symbols: CRKL
Immunogen: Synthesized peptide derived from human Crk-L around the phosphorylation site of Y207.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-CrkL (Tyr207)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CRKL
Gene Alias:
1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12929, 1399, 287942
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P46109, P47941, Q5U2U2
Gene Symbols:
CRKL
Immunogen:
Synthesized peptide derived from human Crk-L around the phosphorylation site of Y207.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG