PA548231

SIK3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA548231-Each-of-1 In Stock ₹ 44,705.10

PA548231 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SIK3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SIK3

Gene Alias

5730525O22Rik; 9030204A07Rik; AI447252; AI846254; AI849445; Kiaa0999; L19; mKIAA0999; QSK; Salt-inducible kinase 3; serine/threonine-protein kinase QSK; Serine/threonine-protein kinase SIK3; SIK family kinase 3; SIK3; SIK-3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

23387

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q9Y2K2

Gene Symbols

SIK3

Immunogen

KLH conjugated synthetic peptide between 1233-1263 amino acids from the C-terminal region of human KIAA0999.

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • SIK3 (QSK) is a serine/threonine-protein kinase, belongs to QIK subfamily
  • The phosphorylation of SIK3 by LKB1 through the 14-3-3 binding enhances its catalytic activity and leads its localization to punctate structures within the cytoplasm
  • Overexpression of SIK3 promotes G1/S cell cycle progression with ovarian cancer
  • There are two sites (H331L and A1103V) were mutated at significant frequency in breast cancer
  • SIK3 is a novel tumor-associated antigen (TAA)
  • SIK3 is a positive regulator of mTOR signaling that functions by triggering the degradation of DEPTOR, an mTOR inhibitor
  • Involved in the dynamic regulation of mTOR signaling in chondrocyte differentiation during skeletogenesis
  • Negatively regulates cAMP signaling pathway possibly by acting on CRTC2/TORC2 and CRTC3/TORC3.

Compare Similar Items

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Img

Thermo Scientific

PA548231

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Antigen:
SIK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIK3

Gene Alias:
5730525O22Rik; 9030204A07Rik; AI447252; AI846254; AI849445; Kiaa0999; L19; mKIAA0999; QSK; Salt-inducible kinase 3; serine/threonine-protein kinase QSK; Serine/threonine-protein kinase SIK3; SIK family kinase 3; SIK3; SIK-3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23387

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9Y2K2

Gene Symbols:
SIK3

Immunogen:
KLH conjugated synthetic peptide between 1233-1263 amino acids from the C-terminal region of human KIAA0999.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA548234

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Antigen:
SASH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SASH1

Gene Alias:
1100001C18Rik; 2500002E12Rik; A330076K04Rik; dJ323M4; dJ323M4.1; KIAA0790; mKIAA0790; PEPE1; Proline-glutamate repeat-containing protein; putative adapter and scaffold protein 1; RGD1566017; SAM and SH3 domain containing 1; SAM and SH3 domain-containing protein 1; Sash1; SH3D6A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23328, 70097

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O94885, P59808

Gene Symbols:
SASH1

Immunogen:
KLH conjugated synthetic peptide between 596-625 amino acids from the Central region of human SASH1.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA548235

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Antigen:
PGCD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GUCY2D

Gene Alias:
cone rod dystrophy 6; CORD5; CORD6; CYGD; guanylate cyclase 2d; guanylate cyclase 2D, membrane (retina-specific); guanylate cyclase 2D, retinal; Guanylate cyclase, olfactory; guanylyl cyclase 2d; guanylyl cyclase D; GUC1A4; GUC2D; GUCY2D; LCA; LCA1; olfactory guanylyl cyclase GC-D; RCD2; RETGC; RETGC1; RETGC-1; retinal guanylate cyclase 1; retinal guanylyl cyclase 1; Rod outer segment membrane guanylate cyclase; ROSGC; ROS-GC; ROS-GC1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
113911, 3000

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P51839, Q02846

Gene Symbols:
GUCY2D

Immunogen:
KLH conjugated synthetic peptide between 540-570 amino acids from the Central region of human GUCY2D.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PA548240

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Antigen:
NBPF8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NBPF8

Gene Alias:
NBPF8; NBPF8P; neuroblastoma breakpoint family member 8; neuroblastoma breakpoint family, member 8; neuroblastoma breakpoint family, member 8, pseudogene; putative neuroblastoma breakpoint family member 8

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
728841

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.31 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q3BBV2

Gene Symbols:
NBPF8

Immunogen:
KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human NBPF8.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG