PA548419

SKA2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA548419-Each-of-1 In Stock ₹ 44,705.10

PA548419 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SKA2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SKA2

Gene Alias

1110001A07Rik; C78640; FAM33A; family with sequence similarity 33, member A; Protein FAM33A; RGD1307084; Ska2; spindle and kinetochore associated complex subunit 2; spindle and kinetochore-associated protein 2; spindle and KT (kinetochore) associated 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

348235

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.35 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q8WVK7

Gene Symbols

SKA2

Immunogen

KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human SKA2.

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Predicted to react with monkey based on sequence homology
  • Upon entry into mitosis, the cell’s microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes
  • Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs
  • A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset
  • Depletion of either SKA1 or SKA2 by siRNA results in the loss of both proteins from the KT, but does not impact overall KT structure
  • Cells depleted of the SKA complex undergo a prolonged checkpoint-dependent delay in a metaphase-like state, indicating the importance of the SKA complex in the maintenance of the metaphase plate and spindle checkpoint silencing
  • SKA2 has also been shown to interact with glucocorticoid receptors and to be involved in glucocorticoid signaling and cell proliferation.

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Thermo Scientific

PA548419

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Antigen:
SKA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKA2

Gene Alias:
1110001A07Rik; C78640; FAM33A; family with sequence similarity 33, member A; Protein FAM33A; RGD1307084; Ska2; spindle and kinetochore associated complex subunit 2; spindle and kinetochore-associated protein 2; spindle and KT (kinetochore) associated 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
348235

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.35 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8WVK7

Gene Symbols:
SKA2

Immunogen:
KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human SKA2.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA548425

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Antigen:
Krt222

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Krt222

Gene Alias:
6330509G02Rik; KA21; keratin 222; keratin 222 pseudogene; keratin 222, type II; keratin-222; Keratin-222 pseudogene; keratin-like protein KRT222; Krt222; KRT222P

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
125113, 268481

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8CCX5, Q8N1A0

Gene Symbols:
Krt222

Immunogen:
KLH conjugated synthetic peptide between 222-250 amino acids from the C-terminal region of human KRT222P.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA548429

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Antigen:
HIST1H2BL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2BC13

Gene Alias:
dJ97D16.4; H2B histone family, member C; H2B/c; H2BFC; HIST1H2BL; histone 1, H2bl; histone cluster 1, H2bl; histone H2B type 1-L; Histone H2B.c; Histone H2Bc

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8340

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q99880

Gene Symbols:
H2BC13

Immunogen:
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BL.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA548435

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Antigen:
PLOD3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLOD3

Gene Alias:
AI414586; bone protein I (BP-I); Galactosylhydroxylysine-glucosyltransferase; LH3; lysine hydroxylase 3; lysyl hydroxlase 3; lysyl hydroxylase 2; lysyl hydroxylase 3; Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3; Plod3; Procollagen galactosyltransferase; Procollagen glucosyltransferase; Procollagen glycosyltransferase; procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3; procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8985

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O60568

Gene Symbols:
PLOD3

Immunogen:
KLH conjugated synthetic peptide between 78-105 amino acids from the N-terminal region of human PLOD3.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG