PA548654

GRAMD1A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA548654-Each-of-1 In Stock ₹ 44,705.10

PA548654 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

GRAMD1A

Classification

Polyclonal

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q8VEF1, Q96CP6

Gene Symbols

GRAMD1A

Immunogen

KLH conjugated synthetic peptide between 267-296 amino acids from the Central region of human GRAMD1A.

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

GRAMD1A

Gene Alias

1300003M23Rik; AI415002; AW547240; D7Bwg0611e; GRAM domain containing 1A; GRAM domain-containing protein 1A; GRAMD1A; KIAA1533; Protein Aster-A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

52857, 57655

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Predicted to react with rat based on sequence homology
  • Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER)
  • Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER
  • Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol
  • In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain
  • At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER
  • May play a role in tumor progression
  • Plays a role in autophagy regulation and is required for biogenesis of the autophagosome (PubMed:31222192)
  • This function in autophagy requires its cholesterol-transfer activity (PubMed:31222192)
  • [UniProt]

Compare Similar Items

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Img

Thermo Scientific

PA548654

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Antigen:
GRAMD1A

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8VEF1, Q96CP6

Gene Symbols:
GRAMD1A

Immunogen:
KLH conjugated synthetic peptide between 267-296 amino acids from the Central region of human GRAMD1A.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
GRAMD1A

Gene Alias:
1300003M23Rik; AI415002; AW547240; D7Bwg0611e; GRAM domain containing 1A; GRAM domain-containing protein 1A; GRAMD1A; KIAA1533; Protein Aster-A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
52857, 57655

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA548672

--


Antigen:
NAPB

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9H115

Gene Symbols:
NAPB

Immunogen:
KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human NAPB.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
NAPB

Gene Alias:
beta soluble NSF attachment protein; beta-soluble NSF attachment protein; beta-soluble NSF attachment protein {ECO:0000250; brain protein 14; brain protein I47; Brp14; b-SNAP; E161; I47; NAPB; napb {ECO:0000250; N-ethylmaleimide sensitive fusion protein attachment protein beta; N-ethylmaleimide-sensitive factor attachment protein beta; N-ethylmaleimide-sensitive factor attachment protein beta {ECO:0000250; N-ethylmaleimide-sensitive factor attachment protein, beta; NSF attachment protein beta; Snapb; SNAP-beta; SNAP-beta {ECO:0000250; SNARE; UniProtKB:P28663}

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
63908

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA548674

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Antigen:
Npr2

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q6VVW5

Gene Symbols:
Npr2

Immunogen:
KLH conjugated synthetic peptide between 480-509 amino acids from the Central region of mouse Npr2.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
Npr2

Gene Alias:
AMDM; ANPb; ANP-B; ANPRB; ANPR-B; atrial natriuretic peptide B-type receptor; atrial natriuretic peptide receptor 2; atrial natriuretic peptide receptor B; atrial natriuretic peptide receptor type B; cn; ECDM; GC-B; GC-B2; GC-B3; guanylate cyclase 2B; guanylate cyclase B; guanylyl cyclase-B; GUC2B; GUCY2B; mNPR-B; natriuretic peptide receptor 2; natriuretic peptide receptor B type; natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B); natriuretic peptide receptor-B; Nppb receptor; NPR2; NPRB; NPR-B; NPRBi; pwe; SNSK

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
230103

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PA548684

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Antigen:
Sgk110

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P0C5K0

Gene Symbols:
Sbk3

Immunogen:
KLH conjugated synthetic peptide between 332-360 amino acids from the C-terminal region of mouse Sgk110.

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
Sbk3

Gene Alias:
Gm1078; Sbk3; Sgk110; SH3 domain binding kinase family member 3; SH3 domain binding kinase family, member 3; SH3-binding domain kinase family member 3; Sugen kinase 110; uncharacterized serine/threonine-protein kinase SBK3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
381835

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid