PA549729

SPAG1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA549729-Each-of-1 In Stock ₹ 44,705.10

PA549729 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SPAG1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPAG1

Gene Alias

CILD28; CT140; epididymis secretory protein Li 268; HEL-S-268; HSD-3.8; Infertility-related sperm protein Spag-1; SP75; SPAG1; sperm associated antigen 1; sperm-associated antigen 1; sperm-associated antigen 1; LOW QUALITY PROTEIN: sperm-associated antigen 1; tetratricopeptide repeat-containing protein; TPIS; TPR-containing protein involved in spermatogenesis

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6674

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q07617

Gene Symbols

SPAG1

Immunogen

Synthetic peptide corresponding to a region derived from 760-774 amino acids of Human sperm associated antigen 1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous level of total SPAG1 protein
  • The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization
  • Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens
  • The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman
  • Furthermore, immunization of female rats with the recombinant human protein reduced fertility
  • This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa
  • Recombinant polypeptide binds GTP and exhibits GTPase activity
  • Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization
  • Two transcript variants of this gene encode the same protein.

Compare Similar Items

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Thermo Scientific

PA549729

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Antigen:
SPAG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPAG1

Gene Alias:
CILD28; CT140; epididymis secretory protein Li 268; HEL-S-268; HSD-3.8; Infertility-related sperm protein Spag-1; SP75; SPAG1; sperm associated antigen 1; sperm-associated antigen 1; sperm-associated antigen 1; LOW QUALITY PROTEIN: sperm-associated antigen 1; tetratricopeptide repeat-containing protein; TPIS; TPR-containing protein involved in spermatogenesis

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6674

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q07617

Gene Symbols:
SPAG1

Immunogen:
Synthetic peptide corresponding to a region derived from 760-774 amino acids of Human sperm associated antigen 1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549731

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Antigen:
AKR1A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKR1A1

Gene Alias:
2610201A18Rik; 3-DG-reducing enzyme; Akr1a1; AKR1A1 protein; Akr1a4; alcohol dehydrogenase; alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; aldo-keto reductase family 1 member A1; aldo-keto reductase family 1, member A1 (aldehyde reductase); aldo-keto reductase family 1, member A4 (aldehyde reductase); ALDR1; ALR; ARM; DD3; dihydrodiol dehydrogenase 3; epididymis secretory protein Li 6; epididymis secretory sperm binding protein Li 165mP; Glucuronate reductase; Glucuronolactone reductase; HEL-S-165mP; HEL-S-6; MGC12529; MGC1380; OTTHUMP00000009240

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10327, 58810, 78959

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P14550, P51635, Q9JII6

Gene Symbols:
AKR1A1

Immunogen:
Synthetic peptide corresponding to a region derived from 312-324 amino acids of human aldo-keto reductase family 1, member A1 (aldehyde reductase)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549732

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Antigen:
AKR1C1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKR1C1

Gene Alias:
17-beta-HSD 5; 17HSD type 5; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); 20-ALPHA-HSD; 20-alpha-hydroxysteroid dehydrogenase; 2-ALPHA-HSD; 3alpha-HSD; Akr1c1; Akr1c6; aldo-keto reductase C; aldo-keto reductase family 1 member C1; aldo-keto reductase family 1, member C1; aldo-keto reductase family 1, member C1 (aldehyde reductase); aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); aldo-keto reductase family 1, member C6; C9; chlordecone reductase homolog HAKRC; DD1; DD1/DD2; DDH; DDH1; dihydrodiol dehydrogenase 1; dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase; dihydrodiol dehydrogenase isoform DD1; estradiol 17 beta-dehydrogenase 5; estradiol 17-beta-dehydrogenase (A-specific); H-37; HAKRC; HBAB; hepatic dihydrodiol dehydrogenase; high-affinity

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1645, 307092

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q04828

Gene Symbols:
AKR1C1

Immunogen:
Synthetic peptide corresponding to a region derived from 290-304 amino acids of human aldo-keto reductase family 1, member C1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549733

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Antigen:
NIT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nit2

Gene Alias:
1190017B19Rik; CUA002; D16Ertd502e; epididymis secretory sperm binding protein Li 8a; HEL-S-8a; Nit protein 2; NIT2; nitrilase family member 2; nitrilase family, member 2; nitrilase homolog 2; Omega-amidase NIT2; RGD1310494

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
52633, 56954

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9JHW2, Q9NQR4

Gene Symbols:
Nit2

Immunogen:
Synthetic peptide corresponding to a region derived from 264-276 amino acids of Human itrilase family, member 2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG