PA549775

AKAP3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA549775-Each-of-1 In Stock ₹ 44,705.10

PA549775 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

AKAP3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AKAP3

Gene Alias

A kinase (PRKA) anchor protein 3; AKAP 110; AKAP110; Akap3; AKAP-3; A-kinase anchor protein 110 kDa; A-kinase anchor protein 3; A-kinase anchor protein, 110kDa; A-kinase anchoring protein 3; Cancer/testis antigen 82; CT82; epididymis luminal protein 159; Fibrous Sheath Protein of 95 kDa; fibrousheathin 1; Fibrousheathin I; fibrousheathin-1; FSP95; HEL159; PRKA3; protein kinase A binding protein AKAP 110; Protein kinase A-anchoring protein 3; SOB1; Sperm oocyte-binding protein; sperm oocyte-binding protein 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10566, 11642

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O75969, O88987

Gene Symbols

AKAP3

Immunogen

Synthesized peptide derived from internal of human AKAP3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total AKAP3 protein
  • The type II cAMP-dependent protein kinase (PKA) is a multifunctional kinase with a broad range of substrates
  • Specificity of PKA signaling is mediated by the compartmentalization of the kinase to specific sites within the cell
  • To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins, designated A-kinase anchoring proteins (AKAP)
  • AKAP 3, also known as AKAP 110, FSP95, PRKA3 and SOB1, binds both PKA and PDE4A and functions as a scaffolding protein in spermatozoa to regulate local cAMP concentrations and modulate sperm functions
  • Expression of AKAP 3 in normal tissues is restricted to the testis, where bicarbonate stimulates tyrosine phosphorylation of AKAP 3, thereby increasing its recruitment of PKA
  • AKAP-3 also exhibits high expression in patients with epithelial ovarian cancer (EOC)
  • It demonstrates tumor-restricted expression and appears to be associated with worse overall survival, which make AKAP 3 a potential target for antigen-specific immunotherapy in EOC.

Compare Similar Items

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Thermo Scientific

PA549775

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Antigen:
AKAP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKAP3

Gene Alias:
A kinase (PRKA) anchor protein 3; AKAP 110; AKAP110; Akap3; AKAP-3; A-kinase anchor protein 110 kDa; A-kinase anchor protein 3; A-kinase anchor protein, 110kDa; A-kinase anchoring protein 3; Cancer/testis antigen 82; CT82; epididymis luminal protein 159; Fibrous Sheath Protein of 95 kDa; fibrousheathin 1; Fibrousheathin I; fibrousheathin-1; FSP95; HEL159; PRKA3; protein kinase A binding protein AKAP 110; Protein kinase A-anchoring protein 3; SOB1; Sperm oocyte-binding protein; sperm oocyte-binding protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10566, 11642

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75969, O88987

Gene Symbols:
AKAP3

Immunogen:
Synthesized peptide derived from internal of human AKAP3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549777

--


Antigen:
MYST2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Kat7

Gene Alias:
EC 2.3.1.48; HBO1; HBOa; histone acetyltransferase binding to ORC1; Histone acetyltransferase KAT7; histone acetyltransferase MYST2; K (lysine) acetyltransferase 7; K(lysine) acetyltransferase 7; Kat7; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST histone acetyltransferase 2; MYST protein 2; MYST2; MYST-2; ZC2HC7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11143, 217127, 303470

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O95251, Q5SVQ0, Q810T5

Gene Symbols:
Kat7

Immunogen:
Synthesized peptide derived from internal of human MYST2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549779

--


Antigen:
SIX6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIX6

Gene Alias:
Homeobox protein SIX6; homeodomain protein OPTX2; MCOPCT2; ODRMD; optic homeobox 2; Optx2; sine oculis homeobox 6; sine oculis homeobox homolog 6; sine oculis homeobox protein 6; sine oculis homeobox-like protein 6; sine oculis-related homeobox 6; sine oculis-related homeobox 6 homolog; SIX homeobox 6; Six6; SIX9; Six9 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20476, 314221, 4990

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O95475, Q9QZ28

Gene Symbols:
SIX6

Immunogen:
Synthesized peptide derived from internal of human SIX6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PA549781

--


Antigen:
FES

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FES

Gene Alias:
AI586313; BB137047; c-fes; EC 2.7.10.2; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog; feline sarcoma oncogene; feline sarcoma/Fujinami avian sarcoma oncogene homolog; Fes; FES proto-oncogene, tyrosine kinase; FPS; Oncogene FES, feline sarcoma virus; p93c-fes; Proto-oncogene c-Fes; proto-oncogene c-Fps; proto-oncogene tyrosine-protein kinase Fes/Fps; RGD1564385; tyrosine kinase Fps/Fes; tyrosine-protein kinase Fes/Fps; Variant 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14159, 2242

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P07332, P16879

Gene Symbols:
FES

Immunogen:
Synthesized peptide derived from internal of human FES.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG