PA549791

PFKL Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA549791-Each-of-1 In Stock ₹ 44,705.10

PA549791 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PFKL

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PFKL

Gene Alias

6-phosphofructokinase type B; 6-phosphofructokinase, liver type; AA407869; ATP-dependent 6-phosphofructokinase, liver type; ATP-dependent 6-phosphofructokinase, liver type {ECO:0000255; ATP-PFK; ATP-PFK {ECO:0000255; EC 2.7.1.11; HAMAP-Rule:MF_03184}; K6PL; liver-type 1-phosphofructokinase; Pfkb; PFK-B; Pfkl; Pfk-l; Phosphofructo-1-kinase isozyme B; phosphofructokinase 1; phosphofructokinase, liver; phosphofructokinase, liver type; phosphofructokinase, liver, B-type; phosphohexokinase; phosphohexokinase {ECO:0000255

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18641, 25741, 5211

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P12382, P17858, P30835

Gene Symbols

PFKL

Immunogen

Synthesized peptide derived from C-terminal of human K6PL.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • The antibody detects endogenous levels of total PFKL protein
  • Phosphofructokinase (PFK), a major regulatory enzyme in all cells of the body, catalyzes the metabolism of sugar, and thereby is pivotal in the production of energy to maintain normal cell function
  • In human there are three structural loci controlling PFK: M (muscle), L (liver), and P (platelet) type subunits, which are variably expressed in different tissues; human diploid fibroblasts and leukocytes express all three genes
  • PFK, a tetramer formed by the random association of the products of two separate gene loci to form the five possible tetramers
  • PFKs of muscle and liver are homotetramers of the M and L subunits, respectively
  • Red cells have all five isozymes: M4, M3L, M2L2, ML3, and L4
  • PFK is an allosteric enzyme activated by ADP, AMP, or fructose bisphosphate and inhibited by ATP or citrate
  • PFK catalyzes the key controlling step of glycolytic pathway
  • PFK deficiency can present as mild to life-threatening episodic illness
  • A hallmark sign of this disease is intermittent dark urine, with the color of the urine ranging from orange to dark coffee-brown, which commonly develops following strenuous exercise
  • The mean red cell PFK is elevated in persons with Down syndrome.

Compare Similar Items

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Thermo Scientific

PA549791

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Antigen:
PFKL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PFKL

Gene Alias:
6-phosphofructokinase type B; 6-phosphofructokinase, liver type; AA407869; ATP-dependent 6-phosphofructokinase, liver type; ATP-dependent 6-phosphofructokinase, liver type {ECO:0000255; ATP-PFK; ATP-PFK {ECO:0000255; EC 2.7.1.11; HAMAP-Rule:MF_03184}; K6PL; liver-type 1-phosphofructokinase; Pfkb; PFK-B; Pfkl; Pfk-l; Phosphofructo-1-kinase isozyme B; phosphofructokinase 1; phosphofructokinase, liver; phosphofructokinase, liver type; phosphofructokinase, liver, B-type; phosphohexokinase; phosphohexokinase {ECO:0000255

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18641, 25741, 5211

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P12382, P17858, P30835

Gene Symbols:
PFKL

Immunogen:
Synthesized peptide derived from C-terminal of human K6PL.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549795

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Antigen:
NFYA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NFYA

Gene Alias:
AA407810; CAAT box DNA-binding protein subunit A; CAAT-box DNA binding protein subunit A; CAAT-box DNA-binding protein subunit A; CBF-A; Cbf-b; CCAAT-binding transcription factor subunit A; CCAAT-binding transcription factor subunit B; FLJ11236; HAP2; HAP2 CCAAT-binding protein; nf-y; NFYA; NF-YA; Nuclear transcription factor Y subunit A; nuclear transcription factor Y subunit alpha; nuclear transcription factor Y, alpha; nuclear transcription factor-Y alpha; SEZ10; SEZ-10; Transcription factor NF-Y, A subunit

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18044, 29508, 4800

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P18576, P23511, P23708

Gene Symbols:
NFYA

Immunogen:
Synthesized peptide derived from internal of human NFYA.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549797

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Antigen:
MZF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MZF1

Gene Alias:
myeloid zinc finger 1; Myeloid zinc finger protein 1; Myeloid zinc finger protein 2; myeloid-specific retinoic acid-responsive zinc finger protein; MZF; MZF1; MZF-1; MZF1B; Mzf2; Mzf-2; Zfp121; Zfp98; Zinc finger and SCAN domain-containing protein 6; zinc finger protein 121; Zinc finger protein 42; zinc finger protein 42 (myeloid-specific retinoic acid-responsive); zinc finger protein 98; Znf42; ZSCAN6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109889, 361508, 7593

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P28698

Gene Symbols:
MZF1

Immunogen:
Synthesized peptide derived from N-terminal of human MZF-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA549800

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Antigen:
CMPK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cmpk1

Gene Alias:
0610011D08Rik; CK; CK {ECO:0000255; CMK; Cmpk; CMPK1; cytidine monophosphate (UMP-CMP) kinase 1; cytidine monophosphate (UMP-CMP) kinase 1, cytosolic; cytidine monophosphate kinase; cytidine/uridine monophosphate kinase 1; cytidylate kinase; cytidylate kinase 1; dCMP kinase; dCMP kinase {ECO:0000255; deoxycytidylate kinase; deoxycytidylate kinase {ECO:0000255; EC 2.7.4.14; HAMAP-Rule:MF_03172}; KCY; likely ortholog of H. sapiens UMP-CMP kinase (UMP-CMPK); nucleoside-diphosphate kinase; nucleoside-diphosphate kinase {ECO:0000255; RGD1310116; RP11-511I2.1; Uck; Umk; UMP/CMP kinase; UMP/CMP kinase {ECO:0000255; UMP/CMPK; UMP/CMPK {ECO:0000255; ump-cmp; UMP-CMP kinase; UMP-CMP kinase {ECO:0000255; UMP-CMP kinase 1; UMP-CMPk; UMPK; uridine monophosphate kinase; uridine monophosphate/cytidine monophosphate kinase; uridine monophosphate/cytidine monophosphate kinase {ECO:0000255

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
298410, 51727, 66588

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P30085, Q4KM73, Q9DBP5

Gene Symbols:
Cmpk1

Immunogen:
Synthesized peptide derived from internal of human KCY.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG