PA549845

MAP4K3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA549845-Each-of-1 In Stock ₹ 45,218.46

PA549845 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

MAP4K3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP4K3

Gene Alias

4833416M01Rik; 4833416M07Rik; 9530052P13Rik; germinal center kinase-like kinase; germinal center kinase-related protein kinase; GLK; MAP4K3; MAPK/ERK kinase kinase kinase 3; MAPKKKK3; MEK kinase kinase 3; MEKKK 3; MEKKK3; mitogen activated protein kinase kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase kinase 3; RAB8IPL1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

170920, 225028, 8491

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8IVH8, Q924I2, Q99JP0

Gene Symbols

MAP4K3

Immunogen

Synthesized peptide derived from N-terminal of human MAP4K3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • The antibody detects endogenous levels of total MAP4K3 protein
  • MAP4K3 (also known as GLK) is a member of the STE20 family of serine/threonine protein kinases and contains N-terminal catalytic domain and C-terminal regulatory domain
  • MAP4K3 is upstream of the MEKK1 target and is stimulated by UV radiation and TNF-alpha and can lead to the activation of the JNK signaling pathway
  • MAP4K3 can directly activate PKC-T, during TCR signaling and people with systemic lupus erythematosus show considerable enhanced MAP4K3 expression and activation of PKC-T, and the kinase IKK in T cells
  • MAP4K3 can act as a pro-apoptotic kinase which orchestrates activation of BAX via the concerted posttranscriptional modulation of PUMA, BAD, and BIM
  • The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha
  • The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway
  • Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase 1 (MEKK1)
  • MAP4K3 previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase 3 (MAP4K3).

Compare Similar Items

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Img

Thermo Scientific

PA549845

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Antigen:
MAP4K3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP4K3

Gene Alias:
4833416M01Rik; 4833416M07Rik; 9530052P13Rik; germinal center kinase-like kinase; germinal center kinase-related protein kinase; GLK; MAP4K3; MAPK/ERK kinase kinase kinase 3; MAPKKKK3; MEK kinase kinase 3; MEKKK 3; MEKKK3; mitogen activated protein kinase kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase kinase 3; RAB8IPL1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170920, 225028, 8491

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8IVH8, Q924I2, Q99JP0

Gene Symbols:
MAP4K3

Immunogen:
Synthesized peptide derived from N-terminal of human MAP4K3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549847

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Antigen:
LMTK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LMTK2

Gene Alias:
2900041G10Rik; A330101P12Rik; aatyk2; Apoptosis-associated tyrosine kinase 2; brain-enriched kinase; BREK; CDK5/p35-regulated kinase; cprk; cyclin-dependent kinase 5/p35-regulated kinase; FLJ46659; hBREK; Kiaa1079; kinase phosphatase inhibitor 2; kinase/phosphatase/inhibitor 2; KPI2; KPI-2; KPI-2 protein; Lemur tyrosine kinase 2; LMKT2; LMR2; Lmtk2; PPP1R100; protein phosphatase 1, regulatory subunit 100; serine/threonine-protein kinase KPI-2; Serine/threonine-protein kinase LMTK2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22853, 231876

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q3TYD6, Q8IWU2

Gene Symbols:
LMTK2

Immunogen:
Synthesized peptide derived from internal of human LMTK2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PA549850

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Antigen:
MINK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MINK1

Gene Alias:
B55; FLJ18426; FLJ38123; FLJ94103; GCK family kinase MiNK; hMINK; hMINKbeta; ISK; JLNS; JLNS2; LQT2/5; LQT5; Map4k6; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; MGC33114; MINK; Mink 1; Mink 2; MINK1; misshapen like kinase 1; misshapen/NIK-related kinase; Misshapen/NIKs-related kinase; misshapen-like kinase 1; misshapen-like kinase 1 (zebrafish); mitogen-activated protein kinase kinase kinase kinase 6; Yeast Sps1/Ste20-related kinase 2; Ysk2; ZC3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50488, 50932

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8N4C8, Q9JM52

Gene Symbols:
MINK1

Immunogen:
Synthesized peptide derived from internal of human MAP4K6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549851

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Antigen:
SPIC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Spic

Gene Alias:
AU019198; C76795; Prf; Pu.1-related factor; SPIC; SPI-C; Spi-C transcription factor; Spi-C transcription factor (Spi-1/PU.1 related); Transcription factor Spi-C

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
121599

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8N5J4

Gene Symbols:
Spic

Immunogen:
Synthesized peptide derived from internal of human SPIC.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG