PA549900

GTF3C3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA549900-Each-of-1 In Stock ₹ 44,705.10

PA549900 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

GTF3C3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GTF3C3

Gene Alias

AL022818; general transcription factor 3C polypeptide 3; general transcription factor IIIC subunit 3; general transcription factor IIIC, polypeptide 3; general transcription factor IIIC, polypeptide 3, 102kDa; GTF3C3; im:7136784; LOC553318 protein; TF3C3; TF3C-gamma; TFIIIC 102 kDa subunit; TFIIIC102; TFiiiC2-102; TFIIICgamma; Transcription factor IIIC 102 kDa subunit; Transcription factor IIIC subunit gamma; transcription factor IIIC-gamma subunit

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9330, 98488

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9Y5Q9

Gene Symbols

GTF3C3

Immunogen

Synthesized peptide derived from internal of human TF3C3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total GTF3C3 protein
  • RNA polymerase (pol) III synthesizes tRNA, 5s rRNA, 7SL RNA and U6 snRNA and is overexpressed in many transformed cell lines and tumors in vivo, since cells must duplicate its protein components before division
  • Therefore, in order to maintain rapid growth, cells must produce a high level of Pol III transcribed RNA, which requires the presence of the TFIIIB and TFIIIC2 transcription factor complexes
  • The TFIIIC2 complex is composed of five subunits, TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, that are overexpressed in adenovirus transformed cells as well as in malignant cells in vivo, such as ovarian carcinomas
  • TFIIIC2 recruits RNA pol III and TFIIIB to promoter elements and may be a key component in the deregulation of malignant cells
  • The TFIIIB complex includes the TATA-binding protein (TBP), TFIIB-related factor 1 (BRF1) and TFIIIB, the expression of which are also upregulated in transformed cells
  • In many carcinomas, the tumor suppressors retinoblastoma (RB) and p53 are inactivated, which affects their ability to bind and inactivate the function of TFIIIB.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PA549900

--


Antigen:
GTF3C3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GTF3C3

Gene Alias:
AL022818; general transcription factor 3C polypeptide 3; general transcription factor IIIC subunit 3; general transcription factor IIIC, polypeptide 3; general transcription factor IIIC, polypeptide 3, 102kDa; GTF3C3; im:7136784; LOC553318 protein; TF3C3; TF3C-gamma; TFIIIC 102 kDa subunit; TFIIIC102; TFiiiC2-102; TFIIICgamma; Transcription factor IIIC 102 kDa subunit; Transcription factor IIIC subunit gamma; transcription factor IIIC-gamma subunit

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9330, 98488

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9Y5Q9

Gene Symbols:
GTF3C3

Immunogen:
Synthesized peptide derived from internal of human TF3C3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549902

--


Antigen:
SALF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STON1

Gene Alias:
4921524J06Rik; C86231; Salf; Sblf; STN1; STNB1; STON1; STON1-GTF2A1L; STON1-GTF2A1L protein; STON1-GTF2A1L readthrough; stoned B homolog 1; stoned B/TFIIA-alpha/beta-like factor; stoned B-like factor; stoned-b1; stonin 1; Stonin1; stonin-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11037

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9Y6Q2

Gene Symbols:
STON1

Immunogen:
Synthesized peptide derived from C-terminal of human STON1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PA549903

--


Antigen:
HTR2C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HTR2C

Gene Alias:
5ht1c; 5-HT1C; 5-HT-1C; 5HT-1C; 5-HT1c receptor; 5-HT2C; 5-HT-2C; 5HT2C Receptor; 5-HT2C receptor; 5-HT2cR; 5HTR2C; 5-HTR2C; 5-hydroxytryptamine (serotonin) receptor 2C; 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled; 5-hydroxytryptamine receptor 1C; 5-hydroxytryptamine receptor 2C; HGNC:5295; HTR1C; Htr2c; RP11-810O3.1; RP23-15B7.1; serotonin 1c receptor; serotonin 5-HT-1C receptor; serotonin 5-HT-2C receptor; serotonin receptor 2C; SR1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15560, 3358

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P28335, P34968

Gene Symbols:
HTR2C

Immunogen:
Synthesized peptide derived from internal of human 5-HT-2C.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549906

--


Antigen:
CADM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CADM2

Gene Alias:
2900078E11Rik; 9330131D06; A830029E02Rik; Cadm2; Cell adhesion molecule 2; Igdf4d; Igsf4d; immunoglobulin superfamily member 4D; immunoglobulin superfamily, member 4; immunoglobulin superfamily, member 4D; NECL3; Necl-3; nectin-like 3; nectin-like protein 3; Synaptic cell adhesion molecule 2; SynCAM 2; SynCAM2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
239857, 253559, 360687

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q1WIM2, Q8BLQ9, Q8N3J6

Gene Symbols:
CADM2

Immunogen:
Synthesized peptide derived from internal of human CADM2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG