PA550123

PHAX Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA550123-Each-of-1 In Stock ₹ 44,705.10

PA550123 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PHAX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PHAX

Gene Alias

26 kDa resiniferatoxin-binding protein; 2810055C14Rik; 4933427L19Rik; AU018701; AU018854; cytosolic resiniferatoxin-binding protein; D18Ertd65e; p55; PHAX; Phosphorylated adapter RNA export protein; phosphorylated adaptor for RNA export; phosphorylation regulated; RBP-2; RBP-26; resiniferatoxin-binding protein 2; RNA U small nuclear RNA export adapter protein; RNA U, small nuclear RNA export adapter (phosphorylation regulated); RNA U, small nuclear RNA export adaptor; RNA U, small nuclear RNA export adaptor (phosphorylation regulated); Rnuxa; RTX-42

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51808

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9H814

Gene Symbols

PHAX

Immunogen

Synthesized peptide derived from internal of human RNUXA.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • The antibody detects endogenous levels of total PHAX protein
  • A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus
  • Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other
  • Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly
  • It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor
  • The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus
  • Its compartmentalized phosphorylation cycle may also contribute to the directionality of export
  • Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner
  • Plays also a role in the biogenesis of U3 small nucleolar RNA (snoRNA)
  • Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies
  • Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs
  • Binds also to telomerase RNA.

Compare Similar Items

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Img

Thermo Scientific

PA550123

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Antigen:
PHAX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PHAX

Gene Alias:
26 kDa resiniferatoxin-binding protein; 2810055C14Rik; 4933427L19Rik; AU018701; AU018854; cytosolic resiniferatoxin-binding protein; D18Ertd65e; p55; PHAX; Phosphorylated adapter RNA export protein; phosphorylated adaptor for RNA export; phosphorylation regulated; RBP-2; RBP-26; resiniferatoxin-binding protein 2; RNA U small nuclear RNA export adapter protein; RNA U, small nuclear RNA export adapter (phosphorylation regulated); RNA U, small nuclear RNA export adaptor; RNA U, small nuclear RNA export adaptor (phosphorylation regulated); Rnuxa; RTX-42

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51808

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9H814

Gene Symbols:
PHAX

Immunogen:
Synthesized peptide derived from internal of human RNUXA.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PA550124

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Antigen:
SERGEF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SERGEF

Gene Alias:
deafness locus associated putative guanine nucleotide exchange factor; deafness locus-associated putative guanine nucleotide exchange factor; DelGEF; Gef; Gnef; Gnefr; guanine nucleotide exchange factor (RCC1 related); guanine nucleotide exchange factor-related protein; secretion regulating guanine nucleotide exchange factor; secretion-regulating guanine nucleotide exchange factor; Sergef

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26297, 27414

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q80YD6, Q9UGK8

Gene Symbols:
SERGEF

Immunogen:
Synthesized peptide derived from internal of human SERGEF.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PA550125

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Antigen:
Septin-14

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SEPT14

Gene Alias:
14-Sep; 1700016K13Rik; Sept14; septin 14; SEPTIN14; septin-14

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
346288, 74222

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6ZU15, Q9DA97

Gene Symbols:
SEPT14

Immunogen:
Synthesized peptide derived from C-terminal of human SEPT14.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA550128

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Antigen:
PLK5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Plk5

Gene Alias:
6330514A18Rik; FG060302; Inactive serine/threonine-protein kinase PLK5; PLK5; PLK-5; PLK5P; polo like kinase 5; polo-like kinase 5; polo-like kinase 5 pseudogene; polo-like kinase 5, pseudogene; serine/threonine-protein kinase PLK5; SgK384ps

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
126520

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q496M5

Gene Symbols:
Plk5

Immunogen:
Synthesized peptide derived from internal of human PLK5.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG