PA550150

PTPN22 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA550150-Each-of-1 In Stock ₹ 46,245.18

PA550150 - Each of 1

₹ 46,245.18

In Stock

Quantity

1

Base Price: ₹ 46,245.18

GST (18%): ₹ 8,324.132

Total Price: ₹ 54,569.312

Antigen

PTPN22

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ptpn22

Gene Alias

70zpep; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; lymphoid-specific protein tyrosine phosphatase; LyP; LYP1; LYP2; PEP; PEST domain-enriched tyrosine phosphatase; PEST-domain phosphatase; protein tyrosine phosphatase, non-receptor type 22; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non-receptor type 8; Ptpn22; PTPN8; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 22

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19260, 26191, 295338

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P29352, Q9Y2R2

Gene Symbols

Ptpn22

Immunogen

Synthesized peptide derived from Internal of human PTPN22.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total PTPN22 protein
  • The protein tyrosine phosphatase PTPN22 (PTP22, LYP, PEP, formerly PTPN8) is a genetic variant that confers risk of developing diverse human autoimmune diseases such as type 1 diabetes and rheumatoid arthritis
  • The minor allele of a missense SNP in PTPN22 encodes a hematopoietic-specific protein tyrosine phosphatase also known as &quoteLyp.&quote The risk allele is present in about 17% of Caucasian individuals from the general population and in approximately 28% of Caucasian individuals with rheumatoid arthritis; it is thought to disrupt the P1 proline-rich motif that is important for interaction with the Src homology-3 (SH3) domain of CSK (cytoplasmic tyrosine kinase), potentially altering the normal functions of these proteins as negative regulators of T cell activation
  • The interaction between CSK and PTPN22 is highly specific and it is speculated that PTPN22 may be an effector and/or regulator of CSK in T cells and other hematopoietic cells.

Compare Similar Items

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Img

Thermo Scientific

PA550150

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Antigen:
PTPN22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptpn22

Gene Alias:
70zpep; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; lymphoid-specific protein tyrosine phosphatase; LyP; LYP1; LYP2; PEP; PEST domain-enriched tyrosine phosphatase; PEST-domain phosphatase; protein tyrosine phosphatase, non-receptor type 22; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non-receptor type 8; Ptpn22; PTPN8; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 22

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19260, 26191, 295338

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P29352, Q9Y2R2

Gene Symbols:
Ptpn22

Immunogen:
Synthesized peptide derived from Internal of human PTPN22.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550151

--


Antigen:
TUT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TUT1

Gene Alias:
2700038E08Rik; FLJ21850; FLJ22267; FLJ22347; MGC131987; MGC149809; nuclear speckle targeted phosphatidylinositol 4-phosphate 5-kinase type I-alpha regulated-poly(A) polymerase; nuclear speckle-targeted PIPK1A-regulated-poly(A) polymerase; PAP-associated domain-containing 2; PAPD2; poly(A) polymerase associated domain containing 2; RBM21; RNA binding motif protein 21; RNA uridylyltransferase; RNA-binding motif protein 21; RNA-binding protein 21; speckle targeted PIP5K1A-regulated poly(A) polymerase; STARPAP; Star-PAP; terminal uridylyl transferase 1 U6 snRNA-specific; terminal uridylyl transferase 1, U6 snRNA-specific; Tut1; TUTase; TUTase 6; TUTase6; U6 snRNA-specific terminal uridylyltransferase 1; U6 snRNA-specific terminal uridylyltransferase 1; speckle targeted PIP5K1A-regulated poly(A) polymerase; U6 TUTase; U6-TUTase; up-regulated in lung cancer 6; URLC6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64852, 70044

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8R3F9, Q9H6E5

Gene Symbols:
TUT1

Immunogen:
Synthesized peptide derived from internal of human TUT1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PA550152

--


Antigen:
USP11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP11

Gene Alias:
6230415D12Rik; deubiquitinating enzyme 11; mKIAA4085; RP4-659F15.2; Ubiquitin carboxyl-terminal hydrolase 11; ubiquitin carboxyl-terminal hydrolase, X-linked; ubiquitin specific peptidase 11; ubiquitin specific protease 11; ubiquitin thioesterase 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin-specific-processing protease 11; UHX1; USP11

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8237

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P51784

Gene Symbols:
USP11

Immunogen:
Synthesized peptide derived from Internal of human USP11.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550153

--


Antigen:
USP32

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Usp32

Gene Alias:
2900074J03Rik; 3.4.19.12; 6430526O11Rik; AW045245; Deubiquitinating enzyme 32; NY-REN-60; renal carcinoma antigen NY-REN-60; Ubiquitin carboxyl-terminal hydrolase 32; ubiquitin specific peptidase 32; ubiquitin specific protease 32; ubiquitin thioesterase 32; ubiquitin thiolesterase 32; ubiquitin-specific-processing protease 32; USP10; USP32

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84669

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8NFA0

Gene Symbols:
Usp32

Immunogen:
Synthesized peptide derived from internal of human USP32.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG