PA550194

BCL2L15 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA550194-Each-of-1 In Stock ₹ 44,705.10

PA550194 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

BCL2L15

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BCL2L15

Gene Alias

BCL2 like 15; BCL2L15; bcl2-L-15; BCL2-like 15; bcl-2-like protein 15; BCLl2-like 15; Bfk; C1orf178; Gm566; pro-apoptotic Bcl-2 protein; RGD1562344

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

440603

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.4 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q5TBC7

Gene Symbols

BCL2L15

Immunogen

Fusion protein corresponding to a region derived from internal residues of human BCL2-like 15

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total BCL2L15 protein
  • Proteins of the Bcl-2 family are critical regulators of apoptosis
  • Proapoptotic members, like Bax, contain three of the four Bcl-2 homology regions (BH1-3), while BH3-only proteins, like Bim, possess only the short BH3 motif
  • Database searches revealed Bfk, an unusual novel member of the Bcl-2 family that contains a BH2 and BH3 region but not BH1 or BH4
  • Bfk is thus most closely related to Bcl-G(L)
  • It lacks a C-terminal membrane anchor and is cytosolic
  • Enforced expression of Bfk weakly promoted apoptosis and antagonized Bcl-2's prosurvival function
  • Like Bcl-G(L), Bfk did not bind to any Bcl-2 family members, even though its BH3 motif can mediate association with prosurvival proteins
  • Low amounts of Bfk were found in stomach, ovary, bone marrow and spleen, but its level in the mammary gland rose markedly during pregnancy, suggesting that Bfk may play a role in mammary development.

Compare Similar Items

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Thermo Scientific

PA550194

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Antigen:
BCL2L15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCL2L15

Gene Alias:
BCL2 like 15; BCL2L15; bcl2-L-15; BCL2-like 15; bcl-2-like protein 15; BCLl2-like 15; Bfk; C1orf178; Gm566; pro-apoptotic Bcl-2 protein; RGD1562344

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
440603

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q5TBC7

Gene Symbols:
BCL2L15

Immunogen:
Fusion protein corresponding to a region derived from internal residues of human BCL2-like 15

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550195

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Antigen:
AARS2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AARS2

Gene Alias:
AARS2; AARSL; alanine tRNA ligase 2, mitochondrial (putative); alanine--tRNA ligase, mitochondrial; alanine--tRNA ligase, mitochondrial {ECO:0000255; Alanyl-tRNA synthetase; alanyl-tRNA synthetase {ECO:0000255; alanyl-tRNA synthetase 2, mitochondrial; alanyl-tRNA synthetase 2, mitochondrial (putative); alanyl-tRNA synthetase like; alanyl-tRNA synthetase, mitochondrial; alaRS; alaRS {ECO:0000255; bA444E17.1; COXPD8; Gm89; HAMAP-Rule:MF_03133}; Kiaa1270; LKENP; MTALARS; MT-ALARS; probable alanyl-tRNA synthetase, mitochondrial

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
224805, 57505

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q14CH7, Q5JTZ9

Gene Symbols:
AARS2

Immunogen:
Fusion protein corresponding to a region derived from internal residues of human Alanyl-tRNA synthetase 2, mitochondrial

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550197

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Antigen:
KRT81

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KRT81

Gene Alias:
AA589625; ghHb1; ghHkb1; Hair keratin K2.9; hard keratin, type II, 1; HB1; Hb-1; hHAKB2-1; K81; Kb21; keratin 81; keratin 81, type II; keratin complex 2, basic, gene 19; keratin, hair, basic, 1; Keratin, type II cuticular Hb1; keratin-81; Krt2-19; KRT81; KRTHB1; Metastatic lymph node 137 gene protein; MLN 137; MLN137; type II hair keratin Hb1; type II keratin Kb21; type-II keratin Kb21

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3887

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.8 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q14533

Gene Symbols:
KRT81

Immunogen:
Fusion protein corresponding to residues near the N terminal of human keratin 81

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550199

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Antigen:
MUC15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MUC15

Gene Alias:
4732460E09; D730046L02Rik; Muc15; MUC-15; mucin 15; mucin 15, cell surface associated; mucin-15; PAS3; PASIII; UNQ750/PRO1481

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
143662, 269328

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q8C6Z1, Q8N387

Gene Symbols:
MUC15

Immunogen:
Synthesized peptide derived from human mucin 15, cell surface associated protein (aa 180-260)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG