PA550266

SPIN2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550266-Each-of-1 In Stock ₹ 46,245.18

PA550266 - Each of 1

₹ 46,245.18

In Stock

Quantity

1

Base Price: ₹ 46,245.18

GST (18%): ₹ 8,324.132

Total Price: ₹ 54,569.312

Antigen

SPIN2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPIN2B

Gene Alias

BC068162; dJ323P24.2; Spin2; SPIN-2; SPIN2_duplicate; SPIN2B; SPIN-2B; Spin2c; SPIN-2C; Spindlin 2B; spindlin family member 2B; spindlin family, member 2; spindlin family, member 2 duplicate; spindlin family, member 2B; spindlin family, member 2C; spindlin-2; spindlin-2B; Spindlin-2C; spindlin-like protein 2; spindlin-like protein 2B; Spindlin-like protein 2C; TDRD26; telomeric SPIN2 copy

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

278240, 474343

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.1 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q6NVE3, Q9BPZ2

Gene Symbols

SPIN2B, Spin2c

Immunogen

Full length fusion protein of Human SPIN2B

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total SPIN2 protein
  • Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin
  • On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death
  • Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line
  • Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity
  • In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth
  • There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.

Compare Similar Items

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Img

Thermo Scientific

PA550266

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Antigen:
SPIN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPIN2B

Gene Alias:
BC068162; dJ323P24.2; Spin2; SPIN-2; SPIN2_duplicate; SPIN2B; SPIN-2B; Spin2c; SPIN-2C; Spindlin 2B; spindlin family member 2B; spindlin family, member 2; spindlin family, member 2 duplicate; spindlin family, member 2B; spindlin family, member 2C; spindlin-2; spindlin-2B; Spindlin-2C; spindlin-like protein 2; spindlin-like protein 2B; Spindlin-like protein 2C; TDRD26; telomeric SPIN2 copy

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
278240, 474343

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q6NVE3, Q9BPZ2

Gene Symbols:
SPIN2B, Spin2c

Immunogen:
Full length fusion protein of Human SPIN2B

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550267

--


Antigen:
SPDL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPDL1

Gene Alias:
1700018I02Rik; 2600001J17Rik; 2810049B11Rik; AA409762; arsenite-related gene 1 protein; Ccdc99; coiled-coil domain containing 99; coiled-coil domain-containing protein 99; coiled-coil domain-containing protein 99 {ECO:0000255; HAMAP-Rule:MF_03041}; hSpindly; protein Spindly; RGD1306908; Rhabdomyosarcoma antigen MU-RMS-40.4A; rrhabdomyosarcoma antigen protein MU-RMS-40.4A; SPDL1; Spindle apparatus coiled-coil domain-containing protein 1; spindle apparatus coiled-coil domain-containing protein 1 {ECO:0000255; spindle apparatus coiled-coil protein 1; spindly homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54908, 70385

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.8 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q923A2, Q96EA4

Gene Symbols:
SPDL1

Immunogen:
Fusion protein corresponding to residues near the C terminal of human Spindle apparatus coiled-coil protein 1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550268

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Antigen:
Synaptotagmin 3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SYT3

Gene Alias:
AI385753; SIII; synaptotagmin 3; synaptotagmin III; Synaptotagmin3; Synaptotagmin-3; SynaptotagminIII; Syt III; Syt3; SYT-3; SytIII

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84258

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1.9 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9BQG1

Gene Symbols:
SYT3

Immunogen:
Fusion protein corresponding to a region derived from internal residues of human synaptotagmin III

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA550270

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Antigen:
Synaptotagmin 7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SYT7

Gene Alias:
AI851541; B230112P13Rik; IPCA7; IPCA-7; PCANAP7; Prostate cancer-associated protein 7; Protein Syt7; synaptotagmin 7; synaptotagmin VII; Synaptotagmin-7; SYT7; SYT-7; SytVII; SYT-VII

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9066

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O43581

Gene Symbols:
SYT7

Immunogen:
Fusion protein corresponding to a region derived from internal residues of human synaptotagmin VII

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG