PA550388

CYFIP2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA550388-Each-of-1 In Stock ₹ 44,705.10

PA550388 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CYFIP2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CYFIP2

Gene Alias

1500004I01Rik; 6430511D02Rik; AA930218; AU022376; cyfip2; cytoplasmic FMR1 interacting protein 2; cytoplasmic FMR1-interacting protein 2; Kiaa1168; mKIAA1168; p53-inducible protein 121; PIR121

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26999, 76884

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.2 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q5SQX6, Q96F07

Gene Symbols

CYFIP2

Immunogen

Fusion protein corresponding to residues near the C terminal of human cytoplasmic FMR1 interacting protein 2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total CYFIP2 / PIR121 protein
  • CYFIP2 (Cytoplasmic FMR1-interacting protein 2, p53-inducible protein 121) is a 1,278 amino acid protein encoded by the human gene CYFIP2
  • CYFIP2 belongs to the CYFIP family and is involved in T-cell adhesion and p53-dependent induction of apoptosis
  • It interacts with FMR1, FXR1 and FXR2 and is a component of the WAVE1 complex composed of Abi-2, CYFIP2, C3orf10/HSPC300, NAP125 and WASF1/WAVE1
  • Upon binding to activated Rac 1, CYFIP2 causes the complex to dissociate, releasing activated WASF1
  • The CYFIP2 promoter contains a p53-responsive element that confers p53 binding as well as transcriptional activation of a heterologous reporter
  • Induced expression of CYFIP2 is sufficient for caspase activation and cellular apoptosis, reminiscent of p53 activation.

Compare Similar Items

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Thermo Scientific

PA550388

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Antigen:
CYFIP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYFIP2

Gene Alias:
1500004I01Rik; 6430511D02Rik; AA930218; AU022376; cyfip2; cytoplasmic FMR1 interacting protein 2; cytoplasmic FMR1-interacting protein 2; Kiaa1168; mKIAA1168; p53-inducible protein 121; PIR121

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26999, 76884

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q5SQX6, Q96F07

Gene Symbols:
CYFIP2

Immunogen:
Fusion protein corresponding to residues near the C terminal of human cytoplasmic FMR1 interacting protein 2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA550390

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Antigen:
LOXL4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LOXL4

Gene Alias:
4833426I20Rik; FLJ21889; Loxc; LOXL4; Lysyl oxidase homolog 4; lysyl oxidase like 4; lysyl oxidase related C; lysyl oxidase-like 4; lysyl oxidase-like 4 pseudogene; lysyl oxidase-like protein 4; Lysyl oxidase-related protein C

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84171

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q96JB6

Gene Symbols:
LOXL4

Immunogen:
Full length fusion protein of Human LOXL4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA550392

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Antigen:
Dynactin 4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCTN4

Gene Alias:
1110001K06Rik; 4930547K17Rik; C130039E17Rik; DCTN4; Dyn4; dynactin 4; dynactin 4 (p62); dynactin 4 (p62) isoform 1; dynactin 4 (p62) isoform 2; dynactin p62 subunit; dynactin subunit 4; Dynactin subunit p62; hypothetical protein LOC550479; P62; si:ch211-174h24.2; zgc:112431

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51164

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
2.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9UJW0

Gene Symbols:
DCTN4

Immunogen:
Fusion protein corresponding to residues near the C terminal of human dynactin 4 (p62)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA550393

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Antigen:
DCTN5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCTN5

Gene Alias:
4930427E12Rik; b2b315Clo; C78178; dctn5; dynactin 4; dynactin 5; dynactin 5 (p25); dynactin subunit 5; dynactin subunit 5-like protein; dynactin subunit p25; MGC3248 protein; p25; p25 dynactin subunit; RGD1305654; zgc:92842

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84516

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.8 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9BTE1

Gene Symbols:
DCTN5

Immunogen:
Full length fusion protein of Human DCTN5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG