PA550400

EDA2R Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550400-Each-of-1 In Stock ₹ 44,705.10

PA550400 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

EDA2R

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EDA2R

Gene Alias

9430060M22Rik; ectodysplasin A2 isoform receptor; ectodysplasin A2 receptor; EDA2R; EDA-A2 receptor; EDAA2R; EDA-A2R; RGD1564025; Tnfrsf27; Tumor necrosis factor receptor superfamily member 27; tumor necrosis factor receptor superfamily member XEDAR; UNQ2448/PRO5727/PRO34080; X linked ectodysplasin receptor; Xedar; X-linked ectodysplasin-A2 receptor

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

60401

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

2.7 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q9HAV5

Gene Symbols

EDA2R

Immunogen

Fusion protein corresponding to residues near the C terminal of human ectodysplasin A2 receptor

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total EDA2R protein
  • X-linked ectodysplasin-A2 receptor (XEDAR) is a recently isolated member of the tumor necrosis factor receptor family that is highly expressed during embryonic development and binds to ectodysplatin-A2 (EDA-A2)
  • Two predominantly expressed isoforms, XEDAR-s and XEDAR-L, differ by only a 21-amino region at the juxtamembrane region of the cytoplasmic domain
  • Neither isoform possesses a death domain and both have been shown to act mainly through TRAF3 and TRAF6 to activate the NF-kappa-B and JNK pathways
  • Cells transfected with XEDAR and treated with EDA-A2 cause the assembly of a secondary complex containing FADD, caspase-8 and caspase-10, leading to the activation caspase-8 and caspase-3, and finally apoptosis
  • The EDA-A2-induced apoptosis is dependent on caspase-9 activation, as various pharmacological and genetic inhibitors of caspase-8 blocked apoptosis following EDA-A2 treatment.

Compare Similar Items

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Thermo Scientific

PA550400

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Antigen:
EDA2R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EDA2R

Gene Alias:
9430060M22Rik; ectodysplasin A2 isoform receptor; ectodysplasin A2 receptor; EDA2R; EDA-A2 receptor; EDAA2R; EDA-A2R; RGD1564025; Tnfrsf27; Tumor necrosis factor receptor superfamily member 27; tumor necrosis factor receptor superfamily member XEDAR; UNQ2448/PRO5727/PRO34080; X linked ectodysplasin receptor; Xedar; X-linked ectodysplasin-A2 receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
60401

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
2.7 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9HAV5

Gene Symbols:
EDA2R

Immunogen:
Fusion protein corresponding to residues near the C terminal of human ectodysplasin A2 receptor

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA550401

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Antigen:
EID1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EID1

Gene Alias:
21 kDa pRb-associated protein; 2610002K20Rik; C15orf3; CREBBP/EP300 inhibitor 1; CREBBP/EP300 inhibitory protein 1; CRI1; E1A-like inhibitor of differentiation 1; EID; eid1; EID-1; EP300 interacting inhibitor of differentiation 1; EP300-interacting inhibitor of differentiation 1; IRO45620; NB4 apoptosis related protein; ORF12; PNAS-22; PTD014; Rb- and p300-binding protein EID-1; RBP21; retinoblastoma protein-associated protein; RGD1562702

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23741, 58521

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.7 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9DCR4, Q9Y6B2

Gene Symbols:
EID1

Immunogen:
Fusion protein corresponding to residues near the N terminal of human EP300 interacting inhibitor of differentiation 1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PA550402

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Antigen:
eIF3f

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF3F

Gene Alias:
0610037M02Rik; AA409853; deubiquitinating enzyme eIF3f; eIF3 p47; eIF-3-epsilon; eIF3-epsilon; EIF3F; eIF3-p47; Eif3s5; eukaryotic translation initiation factor 3 subunit 5; eukaryotic translation initiation factor 3 subunit 5 epsilon; eukaryotic translation initiation factor 3 subunit F; eukaryotic translation initiation factor 3, subunit 5 (epsilon); eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD); eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa; eukaryotic translation initiation factor 3, subunit F

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
66085, 8665

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.1 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O00303, Q9DCH4

Gene Symbols:
EIF3F

Immunogen:
Fusion protein corresponding to residues near the C terminal of human eukaryotic translation initiation factor 3, subunit F

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA550403

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Antigen:
KIF25

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KIF25

Gene Alias:
KIF25; kinesin family member 25; kinesin-like 3; kinesin-like protein 3; Kinesin-like protein KIF25; KNSL3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3834

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
2 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9UIL4

Gene Symbols:
KIF25

Immunogen:
Fusion protein corresponding to residues near the N terminal of human kinesin family member 25

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG