PA550479

PYGL Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA550479-Each-of-1 In Stock ₹ 44,705.10

PA550479 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PYGL

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PYGL

Gene Alias

glycogen liver; Glycogen phosphorylase, liver form; GPLL; GSD6; Lgp; liver glycogen phosphorylase; phosphorylase, glycogen, liver; PYGL

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5836

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

2 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P06737

Gene Symbols

PYGL

Immunogen

Fusion protein corresponding to residues near the C terminal of human phosphorylase, glycogen, liver

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total PYGL protein
  • This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores
  • This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15
  • Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls
  • Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively
  • The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues
  • In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly
  • Alternative splicing results in multiple transcript variants encoding different isoforms.

Compare Similar Items

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Thermo Scientific

PA550479

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Antigen:
PYGL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PYGL

Gene Alias:
glycogen liver; Glycogen phosphorylase, liver form; GPLL; GSD6; Lgp; liver glycogen phosphorylase; phosphorylase, glycogen, liver; PYGL

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5836

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P06737

Gene Symbols:
PYGL

Immunogen:
Fusion protein corresponding to residues near the C terminal of human phosphorylase, glycogen, liver

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PA550483

--


Antigen:
RAB8A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAB8A

Gene Alias:
AA409338; cell line NK14 derived transforming oncogene; MEL; mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; mel transforming oncogene (RAB8 homolog); oncogene c-mel; Rab8; Rab8a; RAB8A, member RAS oncogene family; ras-associated protein RAB8; ras-related protein Rab-8A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4218

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.7 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P61006

Gene Symbols:
RAB8A

Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human Ras-related protein Rab-8A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA550485

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Antigen:
SLC7A5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC7A5

Gene Alias:
4F2; 4F2 LC; 4F2 light chain; 4F2HC; 4F2LC; 4T2HC; CD98; CD98 light chain; CD98HC; CD98LC; D0H16S474E; D16S469E; E16; hLAT1; integral membrane protein E16; large neutral amino acids transporter 1; large neutral amino acids transporter small subunit 1; LAT1; LAT-1; L-type amino acid transporter 1; MDU1; MP hLAT1; MPE16; NACAE; Protein TA1; SLC7A5; sodium-independent neutral amino acid transporter LAT1; solute carrier family 7 (amino acid transporter light chain, L system), member 5; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5; solute carrier family 7 member 5; Ta1; tumor-associated protein 1; y+ system cationic amino acid transporter

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8140

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q01650

Gene Symbols:
SLC7A5

Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human Solute carrier family 7 member 5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA550486

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Antigen:
NPR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPR1

Gene Alias:
AI893888; ANPa; ANP-A; ANPRA; ANPR-A; atrial natriuretic peptide A-type receptor; atrial natriuretic peptide receptor 1; atrial natriuretic peptide receptor A; atrial natriuretic peptide receptor type A; atrionatriuretic peptide receptor A; Gca; GC-A; Guanylate cyclase A; guanylyl cyclase-A; GUC2A; GUCY2A; natriuretic peptide A type receptor; natriuretic peptide receptor 1; natriuretic peptide receptor A; natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A); Nppa receptor; Npr1; Npra; NPR-A; Pndr; testicular tissue protein Li 20

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18160, 24603, 4881

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P16066, P18293, P18910

Gene Symbols:
NPR1

Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG