PA550506

Urotensin II Receptor Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA550506-Each-of-1 In Stock ₹ 44,705.10

PA550506 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Urotensin II Receptor

Classification

Polyclonal

Conjugate

Unconjugated

Gene

UTS2R

Gene Alias

G protein-coupled receptor 14; GPR14; G-protein coupled receptor 14; G-protein coupled sensory epithelial neuropeptide-like receptor; putative G protein-coupled receptor (SENR); Senr; Uiir; Uii-r; Uii-r1a; UII-receptor; UR2R; UR-2-R; UR-II-R; urotensin 2 receptor; urotensin II receptor; Urotensin-2 receptor; UT-II; UTIIR; UTR; UTR2; Uts2r

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2837

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

0.8 mg/mL

Formulation

PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q9UKP6

Gene Symbols

UTS2R

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human urotensin 2 receptor

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody detects endogenous levels of total UTS2R / GPR14 protein
  • The Urotensin-II receptor has been reported to be expressed at high levels in the heart and pancreas and also in artery and smooth muscle
  • Low transcript levels have been identified in brain, particularly in thalamus, and superior occipital gyrus
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

Show Difference

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Thermo Scientific

PA550506

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Antigen:
Urotensin II Receptor

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UTS2R

Gene Alias:
G protein-coupled receptor 14; GPR14; G-protein coupled receptor 14; G-protein coupled sensory epithelial neuropeptide-like receptor; putative G protein-coupled receptor (SENR); Senr; Uiir; Uii-r; Uii-r1a; UII-receptor; UR2R; UR-2-R; UR-II-R; urotensin 2 receptor; urotensin II receptor; Urotensin-2 receptor; UT-II; UTIIR; UTR; UTR2; Uts2r

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2837

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.8 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9UKP6

Gene Symbols:
UTS2R

Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human urotensin 2 receptor

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PA550509

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Antigen:
KCNH8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Kcnh8

Gene Alias:
C130090D05Rik; ELK; ELK channel 3; ELK1; Elk3; ether-a-go-go-like potassium channel 1; ether-a-go-go-like potassium channel 3; Ets-1; hElk1; Kcnh8; Kv12.1; potassium channel, voltage gated eag related subfamily H, member 8; potassium voltage-gated channel subfamily H member 8; potassium voltage-gated channel, subfamily H (eag-related), member 8; potassium voltage-gated channel, subfamily H, member 8; voltage-gated potassium channel subunit Kv12.1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
131096

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q96L42

Gene Symbols:
Kcnh8

Immunogen:
Synthetic peptide corresponding to residues near the C terminal of human potassium voltage-gated channel, subfamily H (eag-related), member 8

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA550510

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Antigen:
HOXA4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HOXA4

Gene Alias:
AV206827; Dfd-like protein; homeo box A4; homeobox A4; homeobox protein Hox-1.4; Homeobox protein Hox-1D; homeobox protein Hox-A4; homeobox protein Hox-A4-like; homeobox protein MH-3; HOX1; Hox-1.4; Hox-1.4-like protein; Hox-14; HOX1D; Hoxa4; Hoxa-4; LOC100912525

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3201

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q00056

Gene Symbols:
HOXA4

Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human homeobox A4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA550511

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Antigen:
ING1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ING1

Gene Alias:
2610028J21Rik; AA407184; AI875420; growth inhibitor ING1; growth inhibitory protein ING1; ING1; inhibitor of growth family member 1; inhibitor of growth family, member 1; inhibitor of growth protein 1; mING1h; p24ING1c; p33; p33ING; p33ING1; p33ING1b; p33ING1c; p37Ing1b; p47; p47ING1a; tumor suppressor ING1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26356, 3621

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1.6 mg/mL

Formulation:
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9QXV3, Q9UK53

Gene Symbols:
ING1

Immunogen:
Synthetic peptide corresponding to residues near the N terminal of human inhibitor of growth family, member 1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG